Effect of 1,064-nm Nd:YAG laser therapy on GCF IL-1? and MMP-8 levels in patients with chronic periodontitis

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dc.contributor.authorEltas, Abubekir
dc.contributor.authorOrbak, Recep
dc.date.accessioned2024-08-04T20:36:00Z
dc.date.available2024-08-04T20:36:00Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the long-term effects of a combined periodontal treatment of scaling and root planing (SRP) and Nd:YAG laser (NDL) in chronic periodontitis (CP) patients. This was accomplished by determining the periodontal indices and the interleukin-1beta (IL-1 beta) and matrix metalloproteinase-8 (MMP-8) levels of the gingival crevicular fluid (GCF). This study was performed according to a random split-mouth-design, controlled clinical trial for sulcular debridement on 40 teeth from 20 patients with generalized moderate chronic periodontitis. The periodontal healing outcomes were compared after periodontal treatment with either SRP + NDL at 1 W (test side) or SRP (control side). Plaque index (PI), gingival index (GI), probing pocket depth (PPD), and clinical attachment level (CAL) were recorded, and samples of gingival crevicular fluid (GCF) were taken at baseline and post-therapy (3 and 9 months after treatment). The GCF samples were analyzed for IL-1 beta and MMP-8. There was postoperative improvement of all clinical parameters in both groups, but test side GI, PPD, and CAL recovery was higher than that of the control side (p < 0.05). Although levels of IL-1 beta and MMP-8 in GCF after treatment were lower in the test side than the control side, there was not a statistically significant difference (p > 0.05). In the long term, we found that SRP + NDL treatment of periodontal pockets was more effective than SRP alone in reducing PPD, CAL, GI, and GCF values.en_US
dc.identifier.doi10.1007/s10103-011-0939-5
dc.identifier.endpage550en_US
dc.identifier.issn0268-8921
dc.identifier.issue3en_US
dc.identifier.pmid21614479en_US
dc.identifier.scopus2-s2.0-84863423788en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage543en_US
dc.identifier.urihttps://doi.org/10.1007/s10103-011-0939-5
dc.identifier.urihttps://hdl.handle.net/11616/95711
dc.identifier.volume27en_US
dc.identifier.wosWOS:000302485500003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer London Ltden_US
dc.relation.ispartofLasers in Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNd:YAG laseren_US
dc.subjectPeriodontal treatmenten_US
dc.subjectGingival crevicular fluiden_US
dc.subjectMatrix metalloproteinase-8en_US
dc.subjectInterleukinen_US
dc.titleEffect of 1,064-nm Nd:YAG laser therapy on GCF IL-1? and MMP-8 levels in patients with chronic periodontitisen_US
dc.typeArticleen_US

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