Effect of renal colic analgesia on oxidative stress parameters

Basit Öğe Kaydı
dc.authoridTurtay, Muhammet Gokhan/0000-0002-1728-8237
dc.authoridPolat, Alaadin/0000-0002-6920-3856
dc.authoridOguzturk, Hakan/0000-0002-9800-1428
dc.authoridPolat, Alaadin/0000-0002-6920-3856
dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authorwosidTurtay, Muhammet Gokhan/ABG-7401-2020
dc.authorwosidPolat, Alaadin/AAA-7171-2021
dc.authorwosidoguzturk, hakan/Q-6242-2019
dc.authorwosidOguzturk, Hakan/AAC-3915-2021
dc.authorwosidPolat, Alaadin/Q-4052-2018
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.contributor.authorTurtay, Muhammet Gokhan
dc.contributor.authorOguzturk, Hakan
dc.contributor.authorColak, Cemil
dc.contributor.authorPolat, Alaadin
dc.contributor.authorTasdemir, Cemal
dc.date.accessioned2024-08-04T20:32:37Z
dc.date.available2024-08-04T20:32:37Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOur aim in this study is to investigate serum oxidative stress parameters before and after fentanyl analgesia in renal colic which is a severe pain condition and to reveal if there is correlation between fentanyl analgesia and serum oxidative stress parameters in renal colic pain. Thirty two male patients, aged 18 - 65, (mean age 40.7 +/- 14.9) who applied to our hospital with the complaint of flank pain and were diagnosed with renal colic were accepted to study. Blood samples were taken from the patients who were diagnosed with renal colic as a result of physical examination and tests (urine analysis, plain radiography, ultrasonography, computed tomography) Pain management of the patients was carried out. Fentanyl (50 - 150 mu g), an opioid analgesic, was used in all patients. When patients stated that the pain was definitely gone through, the blood samples were taken again. Blood samples were taken from each participant twice, before and after the analgesic. Malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) levels were measured from the blood taken. Statistical analysis of the levels which were obtained from before and after the fentanyl treatment was carried out. There were increases in CAT (P < 0.001), SOD (P = 0.002), MDA (P < 0.001), and GPx (P = 0.28) activities in response after analgesic administration in the patients. In our study, the treatment of renal colic pain with fentanyl, an opioid analgesic, led to significant increases in the levels of SOD and CAT, which are antioxidant enzymes.en_US
dc.identifier.endpage3163en_US
dc.identifier.issn1992-2248
dc.identifier.issue20en_US
dc.identifier.scopus2-s2.0-78649415422en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage3160en_US
dc.identifier.urihttps://hdl.handle.net/11616/95191
dc.identifier.volume5en_US
dc.identifier.wosWOS:000284280300016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.relation.ispartofScientific Research and Essaysen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRenal colicen_US
dc.subjectoxidative stressen_US
dc.subjectanalgesicen_US
dc.titleEffect of renal colic analgesia on oxidative stress parametersen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu