Prevalence of the Helicobacter pylori in the tonsils and adenoids

dc.authoridBayindir, Tuba/0000-0003-4150-5016
dc.authoridOTLU, BARIS/0000-0002-6220-0521;
dc.authorwosidKALCIOGLU, Mahmut Tayyar/I-5884-2013
dc.authorwosidBayindir, Tuba/ABG-9517-2020
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.authorwosidToplu, Yuksel/AAA-3133-2021
dc.authorwosidYAKUPOGULLARI, YUSUF/F-3966-2011
dc.authorwosidKalcioglu, M. Tayyar/JAC-1515-2023
dc.contributor.authorBayindir, Tuba
dc.contributor.authorToplu, Yuksel
dc.contributor.authorOtlu, Baris
dc.contributor.authorYakupogullari, Yusuf
dc.contributor.authorYildirim, Ozge
dc.contributor.authorKalcioglu, Mahmut Tayyar
dc.date.accessioned2024-08-04T20:40:14Z
dc.date.available2024-08-04T20:40:14Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. Objective: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis. Methods: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients and patients' serum by using polymerase chain reaction. Results: Hp IgG was detected in 57 (89%) patients' serum. A total of seven tissue samples from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two were tonsil tissues. All polymerase chain reaction positive samples were also positive for the cytotoxin-associated gene, which is a virulence determinant for the organism. Conclusion: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas. (C) 2015 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.en_US
dc.identifier.doi10.1016/j.bjorl.2014.08.018
dc.identifier.endpage311en_US
dc.identifier.issn1808-8694
dc.identifier.issn1808-8686
dc.identifier.issue3en_US
dc.identifier.pmid25900719en_US
dc.identifier.scopus2-s2.0-84929956230en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage307en_US
dc.identifier.urihttps://doi.org/10.1016/j.bjorl.2014.08.018
dc.identifier.urihttps://hdl.handle.net/11616/96793
dc.identifier.volume81en_US
dc.identifier.wosWOS:000356908500014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacialen_US
dc.relation.ispartofBrazilian Journal of Otorhinolaryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHelicobacter pylorien_US
dc.subjectReservoirsen_US
dc.subjectAdenoidsen_US
dc.subjectPalatine tonsilen_US
dc.titlePrevalence of the Helicobacter pylori in the tonsils and adenoidsen_US
dc.typeArticleen_US

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