New-onset diabetes mellitus after liver transplantation in the patients with acute liver failure

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridTopaloğlu, Ömercan/0000-0003-3703-416X
dc.authoridNuransoy Cengiz, Ayse/0000-0001-9133-8602
dc.authoridSahin, ibrahim/0000-0002-6231-0034
dc.authoridCengiz, Muhammet/0000-0002-2028-9687
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidTopaloğlu, Ömercan/O-5534-2018
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.contributor.authorTopaloglu, Omercan
dc.contributor.authorCengiz, Muhammet
dc.contributor.authorCengiz, Ayse
dc.contributor.authorEvren, Bahri
dc.contributor.authorYologlu, Saim
dc.contributor.authorYilmaz, Sezai
dc.contributor.authorSahin, Ibrahim
dc.date.accessioned2024-08-04T20:49:14Z
dc.date.available2024-08-04T20:49:14Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground To detect the frequency and possible risk factors of new-onset diabetes after liver transplantation in the patients with acute liver failure. The frequency of new-onset diabetes after transplant (NODAT) is 5-30% in liver transplant recipients. We aimed to analyze the frequency and predictors of NODAT in the patients undergoing liver transplantation due to acute liver failure. Methods Adult patients undergoing liver transplantation due to acute liver failure were analyzed retrospectively. The patients with chronic liver failure or diabetes were excluded. We measured pretransplant random blood glucose and posttransplant fasting blood glucose. NODAT was diagnosed according to principally 1st month fasting blood glucose (group 1 < 100, group 2 100-125, group 3 > 125 mg/dL). The participants were subgrouped according to age, gender, body mass index, etiology, antiviral medication, thyroid function, pretransplant random blood glucose, donor type, immunosuppressive drug, common infection, and surgical complication. Results Mean age of total 91 patients was 33.48 (+/- 13.35), and 52.7% (n = 48) of them was female. The ratio of NODAT was 26.98% on the 1st month. NODAT group had a higher pretransplant random blood glucose than the others. Pretransplant hyperglycemia increased the risk of NODAT by 4.065 times (p = 0.018). Conclusion We showed that pretransplant hyperglycemia increased NODAT risk by 4 times, but hypoglycemia did not affect. So, pretransplant hyperglycemia should be controlled also in the patients with acute liver failure as in the patients with chronic liver failure.en_US
dc.identifier.doi10.1007/s13410-021-00922-y
dc.identifier.endpage211en_US
dc.identifier.issn0973-3930
dc.identifier.issn1998-3832
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85099765537en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage205en_US
dc.identifier.urihttps://doi.org/10.1007/s13410-021-00922-y
dc.identifier.urihttps://hdl.handle.net/11616/99725
dc.identifier.volume41en_US
dc.identifier.wosWOS:000609947900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofInternational Journal of Diabetes in Developing Countriesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNODATen_US
dc.subjectAcute liver failureen_US
dc.subjectLiver transplanten_US
dc.subjectPosttransplant diabetesen_US
dc.subjectNew onset diabetesen_US
dc.subjectDiabetes mellitusen_US
dc.titleNew-onset diabetes mellitus after liver transplantation in the patients with acute liver failureen_US
dc.typeArticleen_US

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