Effect of intratechal morphine on postoperative stress response and postoperative analgesic requirements on cardiac patients in major abdominal surgery

Basit Öğe Kaydı
dc.authorscopusid6701613323
dc.authorscopusid6603931556
dc.authorscopusid7004839297
dc.authorscopusid12788181900
dc.authorscopusid7102264810
dc.authorscopusid7004486274
dc.contributor.authorTo?al T.
dc.contributor.authorTürköz A.
dc.contributor.authorDurmuş M.
dc.contributor.authorŞahin S.
dc.contributor.authorYilmaz S.
dc.contributor.authorErsoy M.Ö.
dc.date.accessioned2024-08-04T19:59:42Z
dc.date.available2024-08-04T19:59:42Z
dc.date.issued2000
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study investigated the use of single dose intratechal (IT) morphine on cardiac patients undergoing major abdominal surgery and its effect on postoperative stress response, hemodynamic response and postoperative analgesic requirements. ASA class III 20 patients were randomized to receive either 10 ?g/kg of intratechal morphine or control group. Induction were performed by fentanyl 5 ?g/kg, thiopentone 2-4 mg/kg and vecuronium 0.08 mg/kg and anaesthesia was maintained by 33% N2O/O2 mixture with sevoflurane. There were no significant differences in the serum cortisol, glucose, BUN, creatinine, ALP, ALT, AST, CK, CK-MB concentrations recorded in the two groups pre and postoperatively. Cortisol, CK and CK-MB concentrations increased in both groups postoperatively. Plasma glucose concentrations increased in control group postoperatively. There were no significant differences of hemodynamic parameters between the two groups. Analgesic requirements of control group increased postoperatively comparing IT group. Three patients died postoperatively, other side effects were clinically insignificant. In conclusion IT morphine had no effect upon hemodynamic response, did not inhibit the stress response to surgery perioperatively on cardiac patients but we demonstrated the decrease of the postoperative analgesic requirements.en_US
dc.identifier.endpage499en_US
dc.identifier.issn1016-5150
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-0034490162en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage492en_US
dc.identifier.urihttps://hdl.handle.net/11616/90833
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnalgesic requirementsen_US
dc.subjectIntratechal morphineen_US
dc.subjectMajor abdominal surgeryen_US
dc.subjectStress responseen_US
dc.titleEffect of intratechal morphine on postoperative stress response and postoperative analgesic requirements on cardiac patients in major abdominal surgeryen_US
dc.title.alternativeKalp hastalarinda intratekal morfinin büyük abdominal cerrahi sonrasi stres yanita ve analjezi gereksinimine etkisien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu