Analysis of the association between anxiety and depression levels and oxidative stress levels

dc.contributor.authorSavrun, Atakan
dc.contributor.authorSavrun, Seyda Tuba
dc.contributor.authorGokcen, Emre
dc.contributor.authorAygun, Ali
dc.contributor.authorKasko Arici, Yeliz
dc.contributor.authorTurkarslan, Murat
dc.date.accessioned2022-03-09T14:39:49Z
dc.date.available2022-03-09T14:39:49Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: There is a balance between reactive oxygen species (ROS) and antioxidant systems preventing them in the organism. In cases where this balance is impaired, molecular and cellular functions are negatively affected. Thiol-disulfide homeostasis (TDH) is also affected by this imbalance. It has been reported that the balance between oxidative and anti-oxidative systems is disrupted in individuals with psychiatric diseases such as anxiety and depression. Accordingly, it was aimed to determine the level of TDH in the serum of students who took the oral internship exam.Material and Methods: Volunteer fifth grade students of Medical Faculty, 19 male and 21 female, was included in the study. Of the students included in the study, Beck depression and Beck anxiety, albumin, ischemia-modified albumin (IMA), total thiol (SH + SS), native thiol (SH) and SS levels were measured and SS / SH + SS %, SH / SH + SS % and SS / SH % were calculated before and after the oral internship exam. These data were compared with the association between anxiety and depression level changes before and after the oral internship exam.Results: It was observed that the anxiety levels of the participants before the oral exam decreased in the period after the oral exam (p0.001). It was detected that the level of depression of the participants before the oral exam decreased after the oral exam (p0,05). Conclusion: Oral internship exam of Medical Faculty is a factor increasing anxiety and depression levels of the students. However, no association was found between oral internship exam and TDH parameters.en_US
dc.identifier.citationSavrun, A., Tuba Savrun, S., Aygun, A., Gokcen, E., Kasko Arici, Y., & Turkarslan, M. (2021). Analysis of the association between anxiety and depression levels and oxidative stress levels . Annals of Medical Researchen_US
dc.identifier.urihttps://hdl.handle.net/11616/54952
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAnalysis of the association between anxiety and depression levels and oxidative stress levelsen_US
dc.typeArticleen_US

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