Liver Transplantation With Livers From Octogenarians and a Nonagenarian

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authoridsoyer, haci vural/0000-0003-4271-7467
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidSARICI, KEMAL BARIŞ/ABI-4356-2020
dc.authorwosidsoyer, haci vural/KAM-0073-2024
dc.contributor.authorDirican, A.
dc.contributor.authorSoyer, V.
dc.contributor.authorKoc, S.
dc.contributor.authorYagci, M. A.
dc.contributor.authorSarici, B.
dc.contributor.authorOnur, A.
dc.contributor.authorUnal, B.
dc.date.accessioned2024-08-04T20:40:18Z
dc.date.available2024-08-04T20:40:18Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction. A shortage of deceased donors has compelled the use of extended-criteria donor organs in liver transplantation. The purpose of this study was to evaluate the impact of using deceased donors older than 80 years. Materials and Methods. We retrospectively evaluated 13 patients who received a liver graft from cadaveric donors older than 80 years between December 2007 and March 2014. We analyzed the donor and their recipient characteristics together with morbidity and mortality of recipients. Results. All 13 donors were older than 80 years (median age, 82.7; range, 80-93). There were 9 male and 4 female recipients with an average age of 50.7 (range, 2-65) years. All of the recipients did not have a living donor for liver transplantation. Recipients' mean model for end-stage liver disease (MELD) score was 14.2 (range, 7-20). Graft with macroscopic steatosis was not accepted. Medium follow-up was 19.5 months. The most frequent cause for liver transplantation (LT) was hepatitis B virus (HBV) cirrhosis (8/13 patients). We had 1 case of primary nonfunction, and 4 patients died in 2 weeks after surgery. Of these patients, 2 of them received a split transplant from an 80-year-old cadaver liver. Overall the survival rate after 1 year was 61.5%. Conclusions. Deceased elderly donor usage in LT could expand the donor pool. Liver grafts from donors older than 80 years can be used in necessity or emergency situations. However, care should be taken to avoid early mortality and primary nonfunction. Procedures extending cold ischemia time such as split liver transplantation may increase the risk of primary nonfunction.en_US
dc.identifier.doi10.1016/j.transproceed.2015.04.049
dc.identifier.endpage1325en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid26093710en_US
dc.identifier.scopus2-s2.0-84931431460en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1323en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2015.04.049
dc.identifier.urihttps://hdl.handle.net/11616/96838
dc.identifier.volume47en_US
dc.identifier.wosWOS:000357066800021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGraftsen_US
dc.subjectDonorsen_US
dc.subjectOlderen_US
dc.titleLiver Transplantation With Livers From Octogenarians and a Nonagenarianen_US
dc.typeArticleen_US

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