ARYLATION OF ANILINE AND AMINES BY Pd-(N-HETEROCYCLIC CARBENE) COMPLEXES
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aminoarenes constitute valuable building blocks in organic synthesis and an essential skeleton ubiquitously found in ligands, agrochemicals, and pharmaceuticals. This synopsis presents recent amination methods using nitrogen-heteroatom bonds as a powerful and versatile platform to rapidly synthesize diverse aminoarenes, with transition-metal catalyzed arene C-H amination. The Buchwald-Hartwig amination has been investigated theoretically and experimentally to examine the scope of possible bases under different reaction conditions. We report examples of the palladium NHC (N-heterocyclic carbene) catalyzed amination of aryl halides with anilines and amines in the presence of dimethoxyethane solvent and potassium tertiary-butoxide as a base.
Açıklama
Anahtar Kelimeler
Cross-Coupling Reactions, Olefin Metathesis Catalysts, Palladium Complexes, Suzuki-Miyaura, Structural-Characterization, Metal-Complexes, Amination, Halides, Aryl, Ligands
Kaynak
Heterocycles
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
94
Sayı
8
