Unusual complication in patient with Gardner's syndrome: Coexistence of triple gastrointestinal perforation and lower gastrointestinal bleeding: A case report and review of literature

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dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridKoc, Cemalettin/0000-0002-5676-6772
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidKoc, Cemalettin/B-6430-2018
dc.contributor.authorAkbulut, Sami
dc.contributor.authorKoc, Cemalettin
dc.contributor.authorDirican, Abuzer
dc.date.accessioned2024-08-04T20:45:45Z
dc.date.available2024-08-04T20:45:45Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractGardner's syndrome (GS) is a rare syndrome with autosomal dominant inheritance, which is characterized by multiple intestinal polyps, dental anomalies, desmoid tumors, and soft tissue tumors. All gastrointestinal symptoms seen in GS are associated with the underlying familial adenomatosis polyposis and abdominal desmoid tumors, with the most common symptoms being anemia, lower gastrointestinal bleeding, abdominal pain, diarrhea, obstruction, and mucous defecation. To our best knowledge, no case of GS that has presented with gastrointestinal perforation and bleeding has ever been reported in the English language medical literature. A 37-year-old male who had been diagnosed with GS five years earlier was referred to our clinic for lower gastrointestinal bleeding. Despite the absence of a bleeding focus on conventional angiography, the patient was operated on with laparotomy, due to the persistence of both signs and symptoms of mild peritonitis. On the laparotomy, the patient was noted to have areas of perforation in the duodenum, splenic flexura, and midrectum. The third and fourth part of the duodenum, the proximal 15 cm segment of the jejunum, a 10 cm segment of the terminal ileum, the whole colon, and the upper and middle rectum were resected, and duodenojejunal side-to-side anastomosis and terminal ileostomy were performed. The histopathological analysis of the large mass measuring 30 cm x 20 cm was reported as a desmoid tumor. The pathological examination of the tumor foci detected in the colonic specimen revealed poorly differentiated adenosquamous carcinoma.en_US
dc.identifier.doi10.12998/wjcc.v6.i10.393
dc.identifier.endpage397en_US
dc.identifier.issn2307-8960
dc.identifier.issue10en_US
dc.identifier.pmid30283802en_US
dc.identifier.scopus2-s2.0-85062367777en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage393en_US
dc.identifier.urihttps://doi.org/10.12998/wjcc.v6.i10.393
dc.identifier.urihttps://hdl.handle.net/11616/98673
dc.identifier.volume6en_US
dc.identifier.wosWOS:000445744700009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBaishideng Publishing Group Incen_US
dc.relation.ispartofWorld Journal of Clinical Casesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGastrointestinal perforationen_US
dc.subjectGastrointestinal bleedingen_US
dc.subjectAdenosquamous carcinomaen_US
dc.subjectComplicationsen_US
dc.subjectGardner's syndromeen_US
dc.titleUnusual complication in patient with Gardner's syndrome: Coexistence of triple gastrointestinal perforation and lower gastrointestinal bleeding: A case report and review of literatureen_US
dc.typeReview Articleen_US

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