Effect of water extract of Turkish propolis on tuberculosis infection in guinea-pigs

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dc.authoridKutlu, Nurettin Onur/0000-0002-3306-6570
dc.authoridHacievliyagil, Suleyman Savas/0000-0002-2572-1870
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authoridAYDIN, Nasuhi/0000-0003-3145-2432
dc.authorwosidAydin, Nasuhi E/B-6536-2012
dc.authorwosidAYDIN, Nasuhi Engin/L-1607-2019
dc.authorwosidKutlu, Nurettin Onur/AAW-6196-2021
dc.authorwosidHacievliyagil, Suleyman Savas/ABI-7307-2020
dc.authorwosidAYDIN, Nasuhi/O-9043-2016
dc.contributor.authorYildirim, Z
dc.contributor.authorHacievliyagil, S
dc.contributor.authorKutlu, NO
dc.contributor.authorAydin, NE
dc.contributor.authorKurkcuoglu, M
dc.contributor.authorIraz, M
dc.contributor.authorDurmaz, R
dc.date.accessioned2024-08-04T20:13:36Z
dc.date.available2024-08-04T20:13:36Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractMycobacterium tuberculosis (H37Rv)-infected guinea-pig model was used to investigate the effect of water extract of propolis (WEP). After subcutaneous inoculation of tubercle bacilli, each animal received oral WEP (n = 9), isoniazid (n = 5) or saline (n = 6) as placebo and were sacrificed 30 days later. Formation of necrosis was less prominent in the group treated with WEP, but was not statistically significant (P > 0.05). The granuloma formation in the same group was more prominent than the placebo and isoniazid groups; however, this finding failed to reach statistical significance by the Kruskal-Wallis test (P > 0.05). These findings suggest that Turkish WEP may have a limited effect on the development of tuberculosis infection in this guinea-pig model. (C) 2003 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.phrs.2003.10.007
dc.identifier.endpage292en_US
dc.identifier.issn1043-6618
dc.identifier.issue3en_US
dc.identifier.pmid14726226en_US
dc.identifier.scopus2-s2.0-0346059434en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage287en_US
dc.identifier.urihttps://doi.org/10.1016/j.phrs.2003.10.007
dc.identifier.urihttps://hdl.handle.net/11616/93702
dc.identifier.volume49en_US
dc.identifier.wosWOS:000188698800013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAcademic Press Ltd- Elsevier Science Ltden_US
dc.relation.ispartofPharmacological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpropolisen_US
dc.subjecttuberculosisen_US
dc.subjectpreventionen_US
dc.subjectguinea-pigen_US
dc.subjectwater extracten_US
dc.titleEffect of water extract of Turkish propolis on tuberculosis infection in guinea-pigsen_US
dc.typeArticleen_US

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