Risk factors and mortality rate in premature babies with acute kidney injury

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dc.authoridElmas, Ahmet Taner/0000-0002-9749-6115
dc.authoridTabel, Yilmaz/0000-0001-7359-4944
dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.authorwosidELMAS, Ahmet Taner/W-4101-2017
dc.authorwosidElmas, Ahmet Taner/ABI-1338-2020
dc.contributor.authorElmas, Ahmet Taner
dc.contributor.authorTabel, Yilmaz
dc.contributor.authorOzdemir, Ramazan
dc.date.accessioned2024-08-04T20:44:25Z
dc.date.available2024-08-04T20:44:25Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackgroundAcute kidney injury (AKI) is a common morbidity in neonatal intensive care units and associated with poor outcome. This study aimed to determine the prevalence of AKI and provide a demographic data and risk factors associated with the mortality and morbidity. MethodsThis is a retrospective study included 105 premature babies. Diagnosis of AKI was based on neonatal KDIGO classification criteria. The babies were stratified into two groups according to AKI status during the hospitalization. Clinical and laboratory characteristics of the AKI group were compared to non-AKI group. ResultsAKI occurred in 21 (20.0%) of 105 premature babies, and mortality rate in these babies was 61.9%. Lower gestational weeks, lower Apgar scores at 5minutes, lower systolic blood pressures, and inotropic supports were independent risk factors for the development of AKI in preterm babies (P<.05, for each). Oliguria, preeclampsia/eclampsia, resuscitation at birth, lower diastolic blood pressure, patent ductus arteriosus (PDA), inotropic support, and furosemide treatment were associated with the mortality (P<.05, for each). ConclusionsPrenatal risk factors and medical interventions are associated with AKI, and AKI is associated with increased morbidity and mortality. Therefore, identification of AKI is very important in this vulnerable population and it should be performed as quickly as possible in all babies who are at high risk for developing of AKI.en_US
dc.identifier.doi10.1002/jcla.22441
dc.identifier.issn0887-8013
dc.identifier.issn1098-2825
dc.identifier.issue7en_US
dc.identifier.pmid29604124en_US
dc.identifier.scopus2-s2.0-85044748485en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1002/jcla.22441
dc.identifier.urihttps://hdl.handle.net/11616/98225
dc.identifier.volume32en_US
dc.identifier.wosWOS:000444952700002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Laboratory Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectacute kidney injuryen_US
dc.subjectneonatal intensive care uniten_US
dc.subjectpremature babiesen_US
dc.titleRisk factors and mortality rate in premature babies with acute kidney injuryen_US
dc.typeArticleen_US

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