The expression of salivary microRNAs in oral lichen planus: Searching for a prognostic biomarker

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dc.authoridafra, narges/0000-0003-4800-6295
dc.contributor.authorSeif, Sepideh
dc.contributor.authorAfra, Narges
dc.contributor.authorDadgar, Esmaeel
dc.contributor.authorEnteghad, Shabnam
dc.contributor.authorArgani, Pendar
dc.contributor.authorAghdasi, Noura
dc.contributor.authorMasouleh, Sahand Saeidpour
dc.date.accessioned2024-08-04T20:51:55Z
dc.date.available2024-08-04T20:51:55Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOral lichen planus (OLP) is a premalignant disease with unknown etiology. It has been demonstrated that inflammation and immune activation play a central role in the pathogenesis of OLP. Various cellular and molecular mechanisms are involved in the pathogenesis of OLP. Studies have shown that 2-7% of OLP patients develop oral squamous cell carcinoma (OSCC). As a result, determining the prognosis of the disease will be promising in preventing oral carcinoma. MicroRNAs are involved in the regulation of cytokine expression and cytokines have a central role in the pathogenesis of OLP. As a result, their evaluation in body fluids may be helpful in assessing the disease's status and progression, and facilitating the treatment process. In this regard, much attention has been paid to the saliva of OLP patients as the sampling is cost-effective and non-invasive. Here, we discuss the potential of miRNAs in predicting the disease severity and progression.en_US
dc.identifier.doi10.1016/j.prp.2022.153923
dc.identifier.issn0344-0338
dc.identifier.issn1618-0631
dc.identifier.pmid35526303en_US
dc.identifier.scopus2-s2.0-85129483302en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.prp.2022.153923
dc.identifier.urihttps://hdl.handle.net/11616/100632
dc.identifier.volume234en_US
dc.identifier.wosWOS:000799953800005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Gmbhen_US
dc.relation.ispartofPathology Research and Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOral lichen planusen_US
dc.subjectMicroRNAen_US
dc.subjectSalivaen_US
dc.subjectBiomarkeren_US
dc.titleThe expression of salivary microRNAs in oral lichen planus: Searching for a prognostic biomarkeren_US
dc.typeReview Articleen_US

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