The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial

dc.contributor.authorGündoğdu, Hülya
dc.contributor.authorKorkmaz Dişli, Zeliha
dc.contributor.authorÇelebi, Nalan
dc.date.accessioned2022-12-21T11:05:23Z
dc.date.available2022-12-21T11:05:23Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractStrabismus surgery is associated with postoperative nausea-vomiting (PONV) and pain. In this prospective-randomized trial we aimed to investigate the effects of intraoperative paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children. Following approval of ethical committee 50 pediatric patients aged between 3-12 physical status of ASA I-II (American Society of Anesthesiology) undergoing strabismus surgery are included in the study between 2012 and 2013 years. Patients were excluded from the study for these following reasons: known allergic history to paracetamol or other non-steroidal anti-inflammatory drugs (NSAID), morphine and other drugs used in the study; asthma; liver or kidney dysfunction and bleeding disorders. Patients were randomized into two following groups: intravenous paracetamol and IV morphine. Demographic data were similar among groups. Nausea, vomiting scales and anti-emetic requirement of the groups were compared at 0.min, 30.min, 2 hrs and 24 hrs. Analysis had shown that there is a significant difference at the 30th minute, there were no significant differences at other time periods. Wong-Baker faces pain rating scale were compared between groups at 0.min, 30.min, 2 hrs and 24 hrs and no significant differences were seen between group (p > 0.05). Analgesic requirement and sedation scores were compared between groups at 0 min, 30 min, 2 hrs and 24 hrs and no significant differences were seen between groups (p < 0.05). It can be concluded that intravenous paracetamol infusion can safely be used as a replacement to opioids in children undergoing strabismus surgery.en_US
dc.identifier.citationGÜNDOĞDU H, DİŞLİ Z, ÇELEBİ N (2022). The effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trial. Medicine Science, 11(2), 496 - 501. 10.5455/medscience.2021.09.317en_US
dc.identifier.doi10.5455/medscience.2021.09.317en_US
dc.identifier.endpage501en_US
dc.identifier.issn2147-0634
dc.identifier.issue2en_US
dc.identifier.startpage496en_US
dc.identifier.trdizinid529674en_US
dc.identifier.urihttps://doi.org/10.5455/medscience.2021.09.317
dc.identifier.urihttps://hdl.handle.net/11616/85888
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/529674
dc.identifier.volume11en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe effect of intravenous paracetamol infusion on postoperative nausea-vomiting and pain following strabismus surgery in children- a randomised controlled trialen_US
dc.typeArticleen_US

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