Long-term mortality outcomes and mortality predictors in patients with myelomeningocele

Basit Öğe Kaydı
dc.contributor.authorDeniz, Sahin Kenan
dc.contributor.authorTurgut, Hatice
dc.contributor.authorDeveci, Fatih
dc.contributor.authorKaya, Hueseyin
dc.contributor.authorGokce, Ismail Kursad
dc.contributor.authorOzdemir, Ramazan
dc.contributor.authorOnal, Selami Cagatay
dc.date.accessioned2026-04-04T13:35:11Z
dc.date.available2026-04-04T13:35:11Z
dc.date.issued2024
dc.departmentİnönü Üniversitesi
dc.description.abstractObjective: Despite advances, myelomeningocele remains a major cause of mortality and disability. This study aims to analyze factors influencing mortality and suggest ways to reduce it. Methods: We reviewed 173 patients who underwent surgery for myelomeningocele from January 2010 to December 2021. Variables affecting mortality were categorized into patient-related and indirectly related factors. Data were collected through patient file reviews and phone interviews with parents. Results: Mortality is influenced by multiple factors: female gender (3.2-fold increase), paraplegia (3.1-fold increase), absence of tethered cord release surgery (9.4-fold increase), scoliosis (4.2-fold increase), and renal failure (5.28-fold increase). Defect size and father's education level also significantly impact mortality. The overall mortality rate was 20.8 %, with hydrocephalus being the leading cause. Conclusion: Mortality and disability in myelomeningocele patients remain high, with over 50 % of deaths being preventable. Effective management could significantly improve mortality rates. Long-term studies are crucial for advancing research in this field.
dc.identifier.doi10.1016/j.clineuro.2024.108577
dc.identifier.issn0303-8467
dc.identifier.issn1872-6968
dc.identifier.orcid0000-0002-3328-4156
dc.identifier.orcid0000-0002-0490-7852
dc.identifier.orcid0000-0001-8952-2865
dc.identifier.orcid0000-0002-9177-6941
dc.identifier.orcid0000-0003-4722-1188
dc.identifier.pmid39383583
dc.identifier.scopus2-s2.0-85205693086
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.clineuro.2024.108577
dc.identifier.urihttps://hdl.handle.net/11616/109676
dc.identifier.volume246
dc.identifier.wosWOS:001332968200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofClinical Neurology and Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250329
dc.subjectLong-term outcome
dc.subjectMortality predictors
dc.subjectMortality rates
dc.subjectMyelomeningocele
dc.titleLong-term mortality outcomes and mortality predictors in patients with myelomeningocele
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu