Blood pressure is normal, but is the heart?
Yükleniyor...
Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sprınger, 233 sprıng st, new york, ny 10013 usa
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
There is no detailed strain analysis of cardiac functions in treated hypertensive pediatric patients. The aim of this study was to evaluate the cardio-protective effects of different drug classes in treated pediatric hypertensive patients.
Sixty non-obese-treated hypertensive patients with preserved left ventricular (LV) systolic function and 45 age-, sex-, and body mass index-matched healthy subjects underwent clinical evaluation, including 24-h ambulatory blood pressure monitoring, standard echocardiographic examination, tissue Doppler imaging, and two-dimensional Speckle Tracking Echocardiography. The patients were divided into two subgroups based on the effects of the drugs on the Renin Angiotensin Aldosterone System. The subgroup hypertension (HT) 1 received angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, and HT 2 subgroup received calcium channel blocker, beta-blocker, or diuretics.
There was no difference between the two groups and subgroups with respect to clinical, demographic, ABPM, ventricular volumes, ejection fraction, and tissue Doppler imaging (TDI) parameters. For patients and controls, respectively, global longitudinal strain was - 18.70 +/- 3.41 versus - 21.01 +/- 3.82 (P < 0.001), and global radial strain was 40.6 +/- 9.8 versus 54.8 +/- 12.8 (P = 0.004). Peak LV twist and peak LV torsion were not significantly different. The patient subgroup analyses with each other revealed no difference in systolic and diastolic myocardial deformation properties.
Strain parameters were reduced in all treated hypertensive children compared to normotensive children, and the various cardiac mechanic parameters were similarly abnormal no matter what type of antihypertensive agent was used.
Açıklama
Anahtar Kelimeler
Speckle trackıng echocardıography, left-ventrıcular hypertrophy, myocardıal deformatıon, arterıal-hypertensıon, systolıc functıon, european-socıety, chıldren, adolescents, guıdelınes, mechanıcs
Kaynak
Pedıatrıc nephrology
WoS Q Değeri
Scopus Q Değeri
Cilt
33
Sayı
9
Künye
Celik, SF. Karakurt, C. Tabel, Y. Elmas, T. Yologlu, S. (2018). Blood pressure is normal, but is the heart?. Cilt:33. Sayı:9. 1585-1591 ss.
