Myocardial necrosis markers in myocardial ischemia reperfusion MI R injury a review

Basit Öğe Kaydı
dc.authoridTR102000en_US
dc.authoridTR229600en_US
dc.authoridTR184256en_US
dc.contributor.authorParlakpınar, Hakan
dc.contributor.authorÖrüm, Mehmet Hamdi
dc.contributor.authorÖzhan, Onural
dc.date.accessioned2017-04-18T07:01:50Z
dc.date.available2017-04-18T07:01:50Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractMyocardial ischemia/reperfusion injury is one of the main causes of morbidity and mortality in the world. This injury is experienced by patients suffering from cardiovascular diseases such as coronary heart diseases and subsequently undergoing reperfusion treatments in order to manage the conditions. Ischemia can be especially detrimental to the heart due to its high energy demand. Several cellular alterations have been observed upon the onset of ischemia. The danger created by cardiac ischemia is somewhat paradoxical in that a return of blood to the tissue, termed reperfusion, can result in further damage. The serum markers of myocardial injury are used to help in establishing the diagnosis of myocardial infarction. Use of various biochemical markers, including lactate dehydrogenase (LDH), creatine kinase (CK) total enzyme activity, CK-MB activity, Myoglobin, CK-MB mass, cardiac troponin I (cTnI), and cardiac troponin T (cTnT) have been investigated for noninvasive assessment of reperfusion. It is hoped that further studies will help refine the clinical use of new biomarkers like high-sensitivity cardiac troponin (hs-cTn) immunoassays in myocardial injury.en_US
dc.identifier.citationParlakpınar, H. Örüm, M. H. Özhan, O. (2017). Myocardial necrosis markers in myocardial ischemia reperfusion MI R injury a review. Medicine Science | International Medical Journal. 6(1):163‐171.en_US
dc.identifier.doi10.5455/medscience.2016.05.8520en_US
dc.identifier.endpage171en_US
dc.identifier.issn2147-0634
dc.identifier.issue1en_US
dc.identifier.startpage163en_US
dc.identifier.urihttps://hdl.handle.net/11616/6687
dc.identifier.volume6en_US
dc.language.isoenen_US
dc.publisherMedicine Science | International Medical Journalen_US
dc.relation.ispartofMedicine Science | International Medical Journalen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMyocardial ischemia-reperfusionen_US
dc.subjectCreatine kinaseen_US
dc.subjectTroponinen_US
dc.subjectMyoglobinen_US
dc.subjectLactate dehydrogenaseen_US
dc.subjectAspartate amino transferaseen_US
dc.titleMyocardial necrosis markers in myocardial ischemia reperfusion MI R injury a reviewen_US
dc.typeArticleen_US

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