Analysis of urine biomarkers for early determination of acute kidney injury in non-septic and non-asphyxiated critically ill preterm neonates

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dc.authoridElmas, Ahmet Taner/0000-0002-9749-6115;
dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.authorwosidElmas, Ahmet Taner/ABI-1338-2020
dc.authorwosidELMAS, Ahmet Taner/W-4101-2017
dc.contributor.authorElmas, A. T.
dc.contributor.authorKaradag, A.
dc.contributor.authorTabel, Y.
dc.contributor.authorOzdemir, R.
dc.contributor.authorOtlu, G.
dc.date.accessioned2024-08-04T20:41:42Z
dc.date.available2024-08-04T20:41:42Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: We designed the present study to test the hypothesis that urinary biomarkers might predict acute kidney injury (AKI) development in non-septic and non-asphyxiated critically ill preterm infants. We evaluated urine (u) sistatin-C (uCys-C), kidney injury molecule-1 (uKIM-1) and neutrophil gelatinase associate lipocaline (uNGAL) as markers of AKI. Methods: Sixty-four preterm infants with gestational age between 28 and 32 weeks were included in this study. Biomarkers were measured on day of life (DOL) 1, 3, and 7. Results: uNGAL levels in the AKI group were significantly higher than in no-AKI group on DOL 1, 3 and 7 (p = 0.016, p = 0.007 and p = 0.0014, respectively). Conclusions: uNGAL is sensitive, early, and noninvasive AKI biomarkers, increasing significantly in non-septic and non-asphyxiated critically ill preterm neonates.en_US
dc.identifier.doi10.3109/14767058.2016.1171311
dc.identifier.endpage308en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue3en_US
dc.identifier.pmid27020372en_US
dc.identifier.scopus2-s2.0-84964489965en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage302en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2016.1171311
dc.identifier.urihttps://hdl.handle.net/11616/97292
dc.identifier.volume30en_US
dc.identifier.wosWOS:000389664200011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute kidney injuryen_US
dc.subjectkidney injury molecule-1en_US
dc.subjectneutrophil gelatinase associate lipocalineen_US
dc.subjectpreterm infantsen_US
dc.subjectsistatin-Cen_US
dc.subjecturineen_US
dc.titleAnalysis of urine biomarkers for early determination of acute kidney injury in non-septic and non-asphyxiated critically ill preterm neonatesen_US
dc.typeArticleen_US

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