Catechol-bearing imidazolium and benzimidazolium chlorides as promising antimicrobial agents

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dc.authoridÖzdemir, İsmail/0000-0001-6325-0216
dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authoridKarataş, Mert Olgun/0000-0001-8500-2088
dc.authorwosidÖzdemir, İsmail/ABI-5192-2020
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidKarataş, Mert Olgun/ABG-7848-2020
dc.contributor.authorKaratas, Mert O.
dc.contributor.authorGunal, Selami
dc.contributor.authorMansur, Ahmet
dc.contributor.authorAlici, Bulent
dc.contributor.authorOzdemir, Ismail
dc.date.accessioned2024-08-04T20:47:14Z
dc.date.available2024-08-04T20:47:14Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractCatechol-containing imidazolium (four) and benzimidazolium chlorides (eight) were synthesized to evaluate their antimicrobial properties. All the compounds were fully characterized using H-1 and C-13 nuclear magnetic resonance, liquid chromatography-mass spectrometry, infrared spectroscopic methods, and elemental analyses. Antimicrobial activities of the compounds were tested against the bacteria Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), Enterococcus faecalis, and the fungal strains Candida albicans and Candida glabrata, and promising results were achieved. The two most important benzyl-substituted benzimidazolium chlorides, 3l and 3k, showed comparable activity to vancomycin against MRSA.en_US
dc.identifier.doi10.1002/ardp.202000013
dc.identifier.issn0365-6233
dc.identifier.issn1521-4184
dc.identifier.issue6en_US
dc.identifier.pmid32301169en_US
dc.identifier.scopus2-s2.0-85083511029en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1002/ardp.202000013
dc.identifier.urihttps://hdl.handle.net/11616/99254
dc.identifier.volume353en_US
dc.identifier.wosWOS:000526691400001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofArchiv Der Pharmazieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantibacterialen_US
dc.subjectantifungalen_US
dc.subjectbenzimidazoliumen_US
dc.subjectcatecholen_US
dc.subjectimidazoliumen_US
dc.titleCatechol-bearing imidazolium and benzimidazolium chlorides as promising antimicrobial agentsen_US
dc.typeArticleen_US

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