Comparison of propofol-alfentanil and propofol-remifentanil anaesthesia in percutaneous nephrolithotripsy

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dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridcicek, muslum/0000-0001-9187-8342
dc.authorwosidcicek, muslum/P-5252-2019
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidcicek, muslum/AGX-0585-2022
dc.contributor.authorCicek, M
dc.contributor.authorKoroglu, A
dc.contributor.authorDemirbilek, S
dc.contributor.authorTeksan, H
dc.contributor.authorErsoy, MO
dc.date.accessioned2024-08-04T20:14:59Z
dc.date.available2024-08-04T20:14:59Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground and objective: Percutaneous nephrolithotripsy (PCNL) is used for the fragmentation and removal of stones from the renal pelvis and renal calyceal systems. We compared the effects of propofol-alfentanil or propofol-remifentanil anaesthesia on haemodynamics, recovery characteristics and postoperative analgesic requirements during percutaneous nephrolithotripsy. Methods: Thirty non-premedicated patients were randomly allocated to receive either propofol-alfentanil (Group A) or propofol-remifentanil (Group R). The loading dose of the study drug was administered over 60 s (alfentanil 10 mu g kg(-1) or remifentanil 1 mu g kg(-1)) followed by a continuous infusion (alfentanil 15 mu g kg(-1) h(-1) or remifentanil 0.15 mu g kg(-1) min(-1)). Propofol was administered until loss of consciousness and maintained with a continuous infusion of 75 mu g kg(-1) min(-1) in both groups. Atracuriurn was given for endotracheal intubation at a dose of 0.5 mg kg(-1) and maintained with a continuous infusion of 0.4 mg kg(-1) h(-1) Mean arterial pressure heart rate, the total amount of propofol, time of recovery of spontaneous ventilation, extubation and eye opening in response to verbal stimulus and analgesic requirement were recorded. Results: In Group A, mean arterial pressure was higher at the first minute in the prone position, and during skin incision and lithotripsy, and heart rate was higher during skin incision and lithotripsy when compared with Group R (P < 0.05). The total amount of propofol did not differ between groups. Time of recovery of spontaneous ventilation, extubation and eye opening were significantly shorter in Group R than Group A (P < 0.05). Conclusions: Both propofol-remifentanil and propofol-alfentanil anaesthesia provided stable haemodynamics during percutaneous nephrolithotripsy, whereas propofol-remifentanil allowed earlier extubation.en_US
dc.identifier.doi10.1017/S0265021505001134
dc.identifier.endpage688en_US
dc.identifier.issn0265-0215
dc.identifier.issue9en_US
dc.identifier.pmid16163915en_US
dc.identifier.scopus2-s2.0-24744456331en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage683en_US
dc.identifier.urihttps://doi.org/10.1017/S0265021505001134
dc.identifier.urihttps://hdl.handle.net/11616/94093
dc.identifier.volume22en_US
dc.identifier.wosWOS:000232261700006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofEuropean Journal of Anaesthesiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectANAESTHETICS, INTRAVENOUS, propofol, alfentanil, remifentanilen_US
dc.subjectSURGICAL PROCEDURES, urological, percutaneous nephrolithotripsyen_US
dc.subjectHAEMODYNAMIC PHENOMENA, blood pressure, heart rateen_US
dc.subjectANAESTHESIA RECOVERY PERIODen_US
dc.titleComparison of propofol-alfentanil and propofol-remifentanil anaesthesia in percutaneous nephrolithotripsyen_US
dc.typeArticleen_US

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