Preparation of Molecularly Imprinted Electrochemical L-Phenylalanine Sensor with p-Toluene Sulfonic Acid Modified Pt Electrode

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dc.authoridBURC, Muammer/0000-0002-9507-7283
dc.authoridTitretir Duran, Serap/0000-0001-8361-9818
dc.authorwosidBURÇ, Muammer/ABF-1434-2021
dc.contributor.authorAlisik, Funda
dc.contributor.authorBurc, Muammer
dc.contributor.authorKoytepe, Suleyman
dc.contributor.authorDuran, Serap Titretir
dc.date.accessioned2024-08-04T20:49:08Z
dc.date.available2024-08-04T20:49:08Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractL-Phenylalanine (L-Phe) sensors were prepared with two steps by modifying the Pt electrode using the molecular imprinting technique. In first step, polymeric films based on p-toluene sulfonic acid (PTSA) were electropolymerized on the Pt electrode in the presence of L-Phe as template molecule. In the second step, L-Phe, the template molecule, was desorbed from the film structure coated on the electrode surface using acid. The surface properties and morphologies of the prepared modified electrodes were checked by SEM analysis technique. These modified electrodes were used for determination of L-Phe by differential pulse voltammetry (DPV). Electrodes obtained by molecular imprinting method showed R-2 = 0.9997 in the concentration range of 2-2000 mu M L-Phe. The limit of detection (LOD) of L-Phe selective electrodes was found as 0.59 mu M and the limit of quantification (LOQ) was 1.77 mu M. The first three repetition result with the same modified electrode was observed as 96.83% and the RSD value was 14.96% for ten replicates. For twenty modified electrodes, reproducibility was obtained as 97.67% stable between first electrode and twentieth electrode, and the RSD value was observed to be 2.33%. According to these results, prepared molecular imprinted electrodes have high repeatability, stability and selectivity for the determination of L-Phe.en_US
dc.description.sponsorshipInonu University Scientific Research Project Unit [FYL-2019-1581]en_US
dc.description.sponsorshipThe authors thank the financial support from the Inonu University Scientific Research Project Unit by Grant BAP (FYL-2019-1581).en_US
dc.identifier.doi10.1149/1945-7111/abcc35
dc.identifier.issn0013-4651
dc.identifier.issn1945-7111
dc.identifier.issue16en_US
dc.identifier.scopus2-s2.0-85097575761en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1149/1945-7111/abcc35
dc.identifier.urihttps://hdl.handle.net/11616/99670
dc.identifier.volume167en_US
dc.identifier.wosWOS:000596103100001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElectrochemical Soc Incen_US
dc.relation.ispartofJournal of The Electrochemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectL-Phenylalanineen_US
dc.subjectPhenylketonuriaen_US
dc.subjectVoltammetryen_US
dc.subjectSensoren_US
dc.subjectMolecularly imprinted electrodeen_US
dc.titlePreparation of Molecularly Imprinted Electrochemical L-Phenylalanine Sensor with p-Toluene Sulfonic Acid Modified Pt Electrodeen_US
dc.typeArticleen_US

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