Effects of Desflurane and Isoflurane on Hepatic and Renal Functions and Coagulation Profile During Donor Hepatectomy

Basit Öğe Kaydı
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridSanli, Mukadder/0000-0003-1009-5536
dc.authoridToprak, Hüseyin İlksen/0000-0001-9293-8116
dc.authoridŞahin, Taylan/0000-0002-9888-6625
dc.authorwosidsahin, taylan/IWD-9406-2023
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidSanli, Mukadder/ABI-8124-2020
dc.authorwosidToprak, Hüseyin İlksen/AAN-4023-2020
dc.authorwosidŞahin, Taylan/AAT-4038-2020
dc.contributor.authorToprak, H. I.
dc.contributor.authorSahin, T.
dc.contributor.authorAslan, S.
dc.contributor.authorKarahan, K.
dc.contributor.authorSanli, M.
dc.contributor.authorErsoy, M. O.
dc.date.accessioned2024-08-04T20:36:03Z
dc.date.available2024-08-04T20:36:03Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description8th Congress of the Turkish-Transplantation-Centers-Coordination-Association (TTCCA) -- OCT 12-16, 2011 -- Antalya, TURKEYen_US
dc.description.abstractWe compared the effect of two inhalation anesthetics desflurane and isoflurane on postoperative hepatic and renal functions as well as coagulation profiles in living donors undergoing right hepatectomy. This study was performed on 80 patients who were randomly allocated to group D (desflurane, n = 40) or group I (isoflurane, n = 40) after Faculty Ethics Committee approval. After induction, isoflurane or desflurane was used with air/oxygen for anesthetic maintenance. The isoflurane or desflurane concentration was set at one minimum alveolar concentration (MAC). Remifentanil was infused for analgesia as well as cisatracurium. Aspartate aminotransferase (AST), alanine aminotransferase (ALT), international normalized. ratio (INR), albumin, total bilirubin, blood urea nitrogen, creatinine, platelet count, and hemoglobin levels were analyzed preoperatively at end of the operation, and on postoperative days (PODs) 1, 2, 3, 5, 7, and 30. Both AST and ALT differed significantly and continually except on POD 30. AST showed significant elevations from the end of the operation to POD 2 and ALT, from the end of the operation to POD 5 in group I compared with group D. INR was significantly higher from the end of the operation to POD 3 in group I and to POD 2 in group D. At the end of the operation as well as on POD 1 and POD 2, INR was significantly increased in group I compared with group D. Albumin level was significantly lower at the end of the operation in both groups, but it was not different. No patient developed hepatic or renal failure. Our study showed better postoperative hepatic tests and INR using desflurane than isoflurane at equivalent. doses of 1 MAC in living donors undergoing right hepatectomy.en_US
dc.description.sponsorshipTurkish Transplantat Ctr Coordinat Assoc (TTCCA)en_US
dc.identifier.doi10.1016/j.transproceed.2012.05.047
dc.identifier.endpage1639en_US
dc.identifier.issn0041-1345
dc.identifier.issue6en_US
dc.identifier.pmid22841233en_US
dc.identifier.scopus2-s2.0-84864414039en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1635en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2012.05.047
dc.identifier.urihttps://hdl.handle.net/11616/95756
dc.identifier.volume44en_US
dc.identifier.wosWOS:000307433400048en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPropofol Anesthesiaen_US
dc.subjectLiver-Donorsen_US
dc.subjectSurgeryen_US
dc.subjectComplicationsen_US
dc.subjectSevofluraneen_US
dc.subjectHalothaneen_US
dc.subjectInjuryen_US
dc.titleEffects of Desflurane and Isoflurane on Hepatic and Renal Functions and Coagulation Profile During Donor Hepatectomyen_US
dc.typeConference Objecten_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu