Anti-aldosterone therapy in congestive heart failure

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dc.authorscopusid7801569300
dc.authorscopusid35821706600
dc.authorscopusid7004312209
dc.contributor.authorKizilkaya N.
dc.contributor.authorKorkmaz M.E.
dc.contributor.authorMuderrisoglu H.
dc.date.accessioned2024-08-04T20:00:37Z
dc.date.available2024-08-04T20:00:37Z
dc.date.issued1994
dc.departmentİnönü Üniversitesien_US
dc.description.abstractApart from the well-defined renal effects, recent studies have shown the direct effects of aldosterone on cardiovascular system. These studies have shown that besides renal receptors, there are also aldosterone receptors in the heart, great vessels and brain. Stimulation of these receptors in mice may cause myocardial fibrosis and vasoconstriction while anti-aldosterone therapy can inhibit these untoward effects. Such therapy probably can also reduce the total mortality in patients with congestive heart failure. More importantly, aldosterone antagonists display these beneficial effects both on high and low blood pressure levels. These observations imply that anti-aldosterone therapy is effective through multiple mechanisms in congestive heart failure.en_US
dc.identifier.endpage52+7en_US
dc.identifier.issn1016-5169
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-0028205601en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage49en_US
dc.identifier.urihttps://hdl.handle.net/11616/90850
dc.identifier.volume22en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAldosterone antagonistsen_US
dc.subjectCongestive heart failureen_US
dc.titleAnti-aldosterone therapy in congestive heart failureen_US
dc.typeReview Articleen_US

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