Tüberkülozda korunma ve bağışıklık
Küçük Resim Yok
Dosyalar
Tarih
2011
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Türkiye Klinikleri
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Özet
Çok eski çağlardan beri bilinen tüberküloz, Mycobacterium tuberculosis'in neden olduğu bulaşıcı bir enfeksiyon hastalığıdır. 1980'li yıllardan itibaren dünya genelinde görülme sıklığındaki artış, korunma ve kontrol önlemlerini daha önemli hale getirmiştir. Aktif tüberkülozu olan ve bulaştırıcı olduğu kabul edilen hastaların saptanması ve tedavi edilmesi, koruyucu ilaç tedavisi gerektiren kişilere tedavi verilmesi, aşılama ve bulaşın önlenmesine yönelik uygulamalar olmak üzere başlıca dört ana hedef tüberkülozdan korunmada oldukça önemlidir. Tüberküloza karşı gelişen doğal ve kazanılmış bağışık yanıt bir bütün olarak düşünülmelidir. Hastalıktan korunmada önemli olduğu kadar, hastalığın patogenezinde de önemli rol oynamaktadır. BCG aşısının koruyuculuğun tartışılır olması, yeni aşı araştırmalarının artmasına neden olmuştur. Sonuç olarak, M. tuberculosis ile konak immün sistem ilişkisi konusunda hala çok bilinmeyen noktaların bulunduğu açıktır. Temaslıların tespiti, koruyucu ilaç tedavisi ve bulaşın önlenmesine yönelik uygulamalar hala korunmada en geçerli yöntemler olarak durmaktadır.
Tuberculosis, a contagious infectious disease caused by Mycobacterium tuberculosis is known since ancient times. As its incidence increases in the world since 1980s, prevention and control measures have become more important. Four main targets; detection and treatment of patients with active and infectious tuberculosis, treatment of patients admitted to the protective treatment given to persons requiring medical treatment, vaccination and prevention of transmission, including are very important in applications for the prevention of tuberculosis.Developing natural and acquired immune response against tuberculosis should be considered as a whole. They are important not only in preventing the disease, but also play an important role in the pathogenesis of the disease. As the effect of protection for BCG vaccine is open to discussion, investigation on new vaccine and vaccination approaches have been increased. As a result, there are still several points that are not known about the relationship between host immune system and M. tuberculosis. The applications toward the detection of contacts, preventive drug treatment, and prevention of transmission have the most current methods.
Tuberculosis, a contagious infectious disease caused by Mycobacterium tuberculosis is known since ancient times. As its incidence increases in the world since 1980s, prevention and control measures have become more important. Four main targets; detection and treatment of patients with active and infectious tuberculosis, treatment of patients admitted to the protective treatment given to persons requiring medical treatment, vaccination and prevention of transmission, including are very important in applications for the prevention of tuberculosis.Developing natural and acquired immune response against tuberculosis should be considered as a whole. They are important not only in preventing the disease, but also play an important role in the pathogenesis of the disease. As the effect of protection for BCG vaccine is open to discussion, investigation on new vaccine and vaccination approaches have been increased. As a result, there are still several points that are not known about the relationship between host immune system and M. tuberculosis. The applications toward the detection of contacts, preventive drug treatment, and prevention of transmission have the most current methods.
Açıklama
Anahtar Kelimeler
Tüberküloz, Mycobacterium tuberculosis, Korunma ve kontrol, Bağışıklık, Tuberculosis, Mycobacterium tuberculosis, Prevention and control, Immunity
Kaynak
Türkiye Klinikleri
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
2
Künye
Bayındır, Y. Kayhan, B. (2011). Tüberkülozda korunma ve bağışıklık. Türkiye Klinikleri. 4 (2), 94-106.
