Characterization of the antioxidant activity, total phenolic content, enzyme inhibition, and anticancer properties of Achillea millefolium L. (yarrow)

Basit Öğe Kaydı
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridKURUCAY, Ali/0000-0002-8816-0425
dc.authoridKARAASLAN, MERVE GOKSIN/0000-0003-2645-808X
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.contributor.authorKaraaslan Ayhan, Nagihan
dc.contributor.authorKaraaslan Tunc, Merve Goksin
dc.contributor.authorNoma, Samir Abbas Ali
dc.contributor.authorKurucay, Ali
dc.contributor.authorAtes, Burhan
dc.date.accessioned2024-08-04T20:51:58Z
dc.date.available2024-08-04T20:51:58Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe antioxidant activity, total phenolic content, enzyme inhibition, anticancer properties of Achillea millefolium L. (yarrow), which is generally consumed by humans as herbal tea, were investigated. Yarrow extracts were prepared with different extraction techniques and solvents and the optimum conditions were determined. When the antioxidant activity and total phenolic content results were evaluated, the best yield was obtained with ultrasound-assisted extraction for all solvents. Moreover, the yields from highest to lowest were methanol, water, and acetonitrile. The enzyme inhibition and anticancer of Achillea millefolium L. extracts using methanol were evaluated. The IC50 values for the inhibition of xanthine oxidase and acetylcholinesterase were 4.974 +/- 0.54 and 21.891 +/- 1.118 mu g/mL, respectively. The extract concentration was determined to be 23.85 mu g/mL for 50% reduction in growth inhibitory activity cell viability (IC50) against breast cancer (MCF-7).en_US
dc.identifier.doi10.1080/10739149.2022.2073369
dc.identifier.endpage667en_US
dc.identifier.issn1073-9149
dc.identifier.issn1525-6030
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85130588426en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage654en_US
dc.identifier.urihttps://doi.org/10.1080/10739149.2022.2073369
dc.identifier.urihttps://hdl.handle.net/11616/100668
dc.identifier.volume50en_US
dc.identifier.wosWOS:000796925600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofInstrumentation Science & Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAchillea millefolium Len_US
dc.subjectantioxidanten_US
dc.subjectinhibitionen_US
dc.subjectanticanceren_US
dc.subjectextractionen_US
dc.titleCharacterization of the antioxidant activity, total phenolic content, enzyme inhibition, and anticancer properties of Achillea millefolium L. (yarrow)en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu