Multiple approaches to assess human health risks from carcinogenic and non-carcinogenic metals via consumption of five fish species froma large reservoir in Turkey

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dc.authoridVarol, Memet/0000-0001-6475-0570
dc.authorwosidVarol, Memet/F-6797-2013
dc.contributor.authorVarol, Memet
dc.contributor.authorSunbul, Muhammet Rasit
dc.date.accessioned2024-08-04T20:44:24Z
dc.date.available2024-08-04T20:44:24Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractKeban Dam Reservoir (KDR), located on the Euphrates River (Turkey), is an internationally important reservoir. In this study, levels of ten metals in 220 muscle samples of five fish species (mangar, common carp, Tigris scraper, Euphrates barbell and trout barb) taken from 11 sampling sites in the KDR were determined and compared with the results of previous studies carried out in other countries and Turkey. In addition, multiple approaches were used to assess human health risks from fish consumption. The significant spatial differences in concentrations of studied metals except As and Ni in Euphrates barbell were not found. However, concentrations of all metals except Cd showed significant seasonal differences. The concentrations of ten metals in fish species were lower than or comparable to those in fish species from other freshwater bodies. The metal concentrations in all fish species were found below the maximum permissible concentrations. No health risks of studied heavy metals on human were found by daily fish intake. The target hazard quotient (THQ) and total THQ values were below 1, which suggests there are no significant non-carcinogenic health risks for fish consumers. The cancer risk values calculated for inorganic arsenic in all fish species except Euphrates barbell did not exceed the 10-6 threshold. The allowable number of fish meals per month can be categorized as safe fish consumption. The results of this study revealed that the consumption of the examined fish species does not pose a significant risk to human health. (C) 2018 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [114Y018]en_US
dc.description.sponsorshipThe Scientific and Technological Research Council of Turkey (TUBITAK) supported this study (Project Number: 114Y018). Special thanks are given to the anonymous reviewers for their constructive comments for improving the manuscript.en_US
dc.identifier.doi10.1016/j.scitotenv.2018.03.218
dc.identifier.endpage694en_US
dc.identifier.issn0048-9697
dc.identifier.issn1879-1026
dc.identifier.pmid29602109en_US
dc.identifier.scopus2-s2.0-85044467233en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage684en_US
dc.identifier.urihttps://doi.org/10.1016/j.scitotenv.2018.03.218
dc.identifier.urihttps://hdl.handle.net/11616/98210
dc.identifier.volume633en_US
dc.identifier.wosWOS:000432475300067en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofScience of The Total Environmenten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMetalsen_US
dc.subjectArsenicen_US
dc.subjectFreshwater fishen_US
dc.subjectRisk assessment methodsen_US
dc.subjectFish consumption advisoriesen_US
dc.titleMultiple approaches to assess human health risks from carcinogenic and non-carcinogenic metals via consumption of five fish species froma large reservoir in Turkeyen_US
dc.typeArticleen_US

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