Can patients with moderate to severe acute respiratory failure from COPD be treated safely with noninvasive mechanical ventilation on the ward?

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dc.authoridGungor, Sinem/0000-0002-1163-125X
dc.authoridÖztaş, Selahattin/0000-0001-7658-1225
dc.authoridYalçınsoy, Murat/0000-0003-3407-7359
dc.authoridOruc, Ozlem/0000-0003-3197-4767
dc.authorwosidGungor, Sinem/GPX-1807-2022
dc.authorwosidGungor, Sinem/AAZ-7783-2021
dc.authorwosidÖztaş, Selahattin/HKW-7272-2023
dc.authorwosidOzmen, Ipek/I-3449-2018
dc.authorwosidAksoy, Emine/M-1562-2019
dc.authorwosidYalçınsoy, Murat/ABI-1421-2020
dc.authorwosidOruc, Ozlem/KEJ-4023-2024
dc.contributor.authorYalcinsoy, Murat
dc.contributor.authorSalturk, Cuneyt
dc.contributor.authorOztas, Selahattin
dc.contributor.authorGungor, Sinem
dc.contributor.authorOzmen, Ipek
dc.contributor.authorKabadayi, Feyyaz
dc.contributor.authorOztim, Aysem Askim
dc.date.accessioned2024-08-04T20:41:48Z
dc.date.available2024-08-04T20:41:48Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: Noninvasive mechanical ventilation (NIMV) usage outside of intensive care unit is not recommended in patients with COPD for severe acute respiratory failure (ARF). We assessed the factors associated with failure of NIMV in patients with ARF and severe acidosis admitted to the emergency department and followed on respiratory ward. Patients and methods: This is a retrospective observational cohort study conducted in a tertiary teaching hospital specialized in chest diseases and thoracic surgery between June 1, 2013 and May 31, 2014. COPD patients who were admitted to our emergency department due to ARF were included. Patients were grouped according to the severity of acidosis into two groups: group 1 (pH= 7.20-7.25) and group 2 (pH= 7.26-7.30). Results: Group 1 included 59 patients (mean age: 70 +/- 10 years, 30.5% female) and group 2 included 171 patients (mean age: 67 +/- 11 years, 28.7% female). On multivariable analysis, partial arterial oxygen pressure to the inspired fractionated oxygen (PaO2/FiO(2)) ratio <200, delta pH value <0.30, and pH value <7.31 on control arterial blood gas after NIMV in the emergency room and peak C-reactive protein were found to be the risk factors for NIMV failure in COPD patients with ARF in the ward. Conclusion: NIMV is effective not only in mild respiratory failure but also with severe forms of COPD patients presenting with severe exacerbation. The determination of the failure criteria of NIMV and the expertise of the team is critical for treatment success.en_US
dc.identifier.doi10.2147/COPD.S104801
dc.identifier.endpage1160en_US
dc.identifier.issn1178-2005
dc.identifier.pmid27330283en_US
dc.identifier.scopus2-s2.0-84973500799en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1151en_US
dc.identifier.urihttps://doi.org/10.2147/COPD.S104801
dc.identifier.urihttps://hdl.handle.net/11616/97363
dc.identifier.volume11en_US
dc.identifier.wosWOS:000377090000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDove Medical Press Ltden_US
dc.relation.ispartofInternational Journal of Chronic Obstructive Pulmonary Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectnoninvasive mechanical ventilationen_US
dc.subjectCOPDen_US
dc.subjectacute respiratory failureen_US
dc.subjectexacerbationen_US
dc.subjectmortalityen_US
dc.titleCan patients with moderate to severe acute respiratory failure from COPD be treated safely with noninvasive mechanical ventilation on the ward?en_US
dc.typeArticleen_US

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