Analysis of an outbreak due to Chryseobacterium meningosepticum in a neonatal intensive care unit

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dc.authoridOTLU, BARIS/0000-0002-6220-0521
dc.authoridTekerekoglu, Mehmet Sait/0000-0001-7284-3427
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.authorwosidTekerekoglu, Mehmet Sait/ABI-8148-2020
dc.contributor.authorTekerekoglu, MS
dc.contributor.authorDurmaz, R
dc.contributor.authorAyan, M
dc.contributor.authorCizmeci, Z
dc.contributor.authorAkinci, A
dc.date.accessioned2024-08-04T20:13:14Z
dc.date.available2024-08-04T20:13:14Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to describe the epidemiological and clinical features of an outbreak due to Chryseobacterium meningosepticum. During a 11-day period, the outbreak was observed among four newborns in a neonatal intensive care unit (NICU) in a teaching hospital. All patients yielded C. meningosepticum in their blood cultures, in addition one was colonised in the throat. Antimicrobial susceptibility assay showed complete resistance to penicillins, cephalosporins, aminoglycosides, imipenem, aztreonam, and tetracycline, sensitivity to ciprofloxacin and trimethoprim-sulfamethoxazole. All patients were empirically treated with amikacin and meropenem. The neonate who was the first to develop sepsis died before the culture result. When C. meningosepticum was identified, antimicrobial therapy was changed to a combination of ciprofloxacin, rifampicin and vancomycin, and three neonates were treated successfully. Environmental screening recovered C. meningosepticum from two venous catheter lines and one nutritional solution that was opened by health care staff and used for two neonates. Arbitrary primed polymerase chain reaction and antibiogram typing indicated that all isolates were epidemiologically related. This study demonstrates that rapid selection of appropriate antibiotics is critical for clinical cure and standard precautions should be reconsidered to limit the spread of this bacterium on the NICU in our hospital.en_US
dc.identifier.endpage63en_US
dc.identifier.issn1121-7138
dc.identifier.issue1en_US
dc.identifier.pmid12578312en_US
dc.identifier.scopus2-s2.0-0037271554en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage57en_US
dc.identifier.urihttps://hdl.handle.net/11616/93485
dc.identifier.volume26en_US
dc.identifier.wosWOS:000180806600008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLuigi Ponzio E Figlioen_US
dc.relation.ispartofMicrobiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChryseobacterium meningosepticumen_US
dc.subjectoutbreaken_US
dc.subjectsepsisen_US
dc.subjectnewbornen_US
dc.subjectAP-PCRen_US
dc.titleAnalysis of an outbreak due to Chryseobacterium meningosepticum in a neonatal intensive care uniten_US
dc.typeArticleen_US

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