Correlation between red cell distribution width and grade of hepatic steatosis and liver enzymes in patients with Non-Alcoholic steatohepatitis

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dc.contributor.authorDoğan, Ali
dc.contributor.authorDoğan, Narin Yıldırım
dc.contributor.authorEkinci, Ömer
dc.contributor.authorKarıncaoğlu, Melih
dc.date.accessioned2024-08-04T19:53:16Z
dc.date.available2024-08-04T19:53:16Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractRed cell distribution width (RDW) is a marker of chronic inflammation. Hepatic diseases are often associated with several hematological complications; therefore, high levels of RDW are seen in hepatic diseases. Given the fact that factors which cause non-alcoholic steatohepatitis such as inflammation, oxidative stress, free oxygen radicals, and inflammatory cytokines may have a role in the discrepancy in the erythrocyte volume, we aimed to investigate the relationship between RDW and hepatic enzymes and Grade of hepatic steatosis. A total of 120 patients with non-alcoholic steatohepatitis using abdominal ultrasonography which was performed by a gastroenterology specialist, were included in the study. Biochemical analysis, complete blood count, other blood tests were performed. Spearman’s Rho correlation test was used to analyze the relationship between the parameters and p value was accepted significant if it’s <0.05. As a result of our study, there was no significant relationship between RDW and liver steatosis degree (p: 0.704). Also, significant relationship was not found between RDW and alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) and lactate dehydrogenase (LDH) ( p values were 0,223, 0,856, 0,318, 0,597, 0,195 consecutively). In our study, we tried to find an answer to if there is a relationship between RDW alterations and inflammation which takes place in the pathogenesis of non-alcoholic steatohepatitis. As a result, we found no significant correlation between the RDW values and the degree of steatosis of liver and also liver enzymes.en_US
dc.identifier.doi10.5455/medscience.2017.06.8710
dc.identifier.endpage131en_US
dc.identifier.issn2147-0634
dc.identifier.issue1en_US
dc.identifier.startpage127en_US
dc.identifier.trdizinid309357en_US
dc.identifier.urihttps://doi.org/10.5455/medscience.2017.06.8710
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/309357
dc.identifier.urihttps://hdl.handle.net/11616/89626
dc.identifier.volume7en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleCorrelation between red cell distribution width and grade of hepatic steatosis and liver enzymes in patients with Non-Alcoholic steatohepatitisen_US
dc.typeArticleen_US

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