Clinicopathological Features of Young Gastric Cancer and New Inflammatory Prognostic Markers

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dc.contributor.authorGülmez, Ahmet
dc.contributor.authorDikilitaş, Mustafa
dc.date.accessioned2024-08-04T19:42:31Z
dc.date.available2024-08-04T19:42:31Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractINTRODUCTION: This study aimed to evaluate the clinicopathologic features of young gastric cancer (GC) patients and to investigate the factors affecting survival (OS). METHODS: In this study, the data of 55 patients diagnosed under the age of 40 were obtained by retrospective evaluation of hospital records. Clinicopathological features and some laboratory parameters of this patient group and new inflammatory prognostic markers (IPM) obtained from these parameters were evaluated. RESULTS: The mean age of the patients in this study was 33 years. The majority of the patients were male. Patients were evaluated according to human C-erbB2 positivity too. The identified patients as positive were only 7% of all patients. Also, the patients were evaluated for platinum sensitivity too. It was found that 30% of the patients were sensitive to platinum treatments. Also, survival times of the patients were evaluated with IPM. Neutrophil-lymphocyte ratio (NLR), mean platelet volume/platelet count, C-reactive protein/albumin ratios were calculated separately. Survival results were analyzed based on the mean values of all 3 prognostic markers. Even though there was a significant numerical difference, no statistical significance was found. DISCUSSION AND CONCLUSION: This study was conducted to examine the clinicopathological features and survival time of young GC patients. Low C-erbB2 positivity and high platinum resistance were found among this patient population. In addition, inflammatory prognostic markers, which were found to be associated with survival in most cancers, were found to cause significant numerical differences in terms of survival in our study.en_US
dc.identifier.doi10.5505/aot.2023.74317
dc.identifier.endpage96en_US
dc.identifier.issn0304-596X
dc.identifier.issn2148-7669
dc.identifier.issue2en_US
dc.identifier.startpage90en_US
dc.identifier.trdizinid1210542en_US
dc.identifier.urihttps://doi.org/10.5505/aot.2023.74317
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1210542
dc.identifier.urihttps://hdl.handle.net/11616/88392
dc.identifier.volume56en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofACTA ONCOLOGICA TURCICAen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleClinicopathological Features of Young Gastric Cancer and New Inflammatory Prognostic Markersen_US
dc.typeArticleen_US

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