Relationship Between Dental Caries and YKL-40 Levels in Saliva

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dc.contributor.authorDuruk, Gulsum
dc.contributor.authorLaloglu, Esra
dc.date.accessioned2024-08-04T20:51:55Z
dc.date.available2024-08-04T20:51:55Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: YKL-40, a new biomarker of localized inflammation, is secreted by macrophages and regulates inflammation and immune responses. The aim of this study was to investigate YKL-40 levels in saliva and compare the level of this mediator in healthy and unhealthy oral cavity. Study design: 80 children (42-girl, 38-boy), aged 6-15 (mean +/- SD: 9.35 +/- 2.08) were included in this cross-sectional study. The children were divided into four groups: Group-I (control, n=20, dmft/DMFT=0), Group-II (n=20, exist of dental caries), Group-III (n=20, exist of advanced dental caries without pulp exposure), and Group-IV (n=20, exist of advanced dental caries with pulp exposure). The dmft/DMFT, dmfs/DMFS, and the number of advanced dental caries according to the ICDAS and pufa/PUFA index were recorded. Saliva was collected and YKL-40 concentrations were measured. Results: The highest level of YKL-40 was obtained in Group IV, followed by Groups III, II, and I, respectively (p<0.01). There was a positive correlation between YKL-40 and the number of caries There were no statistically significant difference in YKL-40 levels in terms of age and gender (p>0.05). Conclusions: The advanced dental caries with pulp exposure may play an important role in the increasing levels of YKL-40 in saliva.en_US
dc.identifier.doi10.17796/1053-4625-46.2.8
dc.identifier.endpage142en_US
dc.identifier.issn1053-4628
dc.identifier.issn1557-5268
dc.identifier.issue2en_US
dc.identifier.pmid35533232en_US
dc.identifier.scopus2-s2.0-85129557749en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage137en_US
dc.identifier.urihttps://doi.org/10.17796/1053-4625-46.2.8
dc.identifier.urihttps://hdl.handle.net/11616/100636
dc.identifier.volume46en_US
dc.identifier.wosWOS:000802170200008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJournal Pedodontics Incen_US
dc.relation.ispartofJournal of Clinical Pediatric Dentistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDental cariesen_US
dc.subjectpulpiten_US
dc.subjectsalivaen_US
dc.subjectYKL-40en_US
dc.titleRelationship Between Dental Caries and YKL-40 Levels in Salivaen_US
dc.typeArticleen_US

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