Routine Histopathologic Examination of Appendectomy Specimens: Retrospective Analysis of 1255 Patients

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dc.authoridsahin, nurhan/0000-0001-9487-1154
dc.authoridBozdag, Zehra/0000-0002-0477-2513
dc.authoridYILMAZ, Mehmet/0000-0002-5710-5263
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authorid, ayse/0000-0001-5259-7193
dc.authorwosidEmre, Arif/JME-3234-2023
dc.authorwosidsahin, nurhan/ABF-8007-2020
dc.authorwosidBozdag, Zehra/AAG-5279-2020
dc.authorwosidYILMAZ, Mehmet/HKM-4739-2023
dc.authorwosidYilmaz, Mehmet/AAF-6095-2021
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorEmre, Arif
dc.contributor.authorAkbulut, Sami
dc.contributor.authorBozdag, Zehra
dc.contributor.authorYilmaz, Mehmet
dc.contributor.authorKanlioz, Murat
dc.contributor.authorEmre, Rabia
dc.contributor.authorSahin, Nurhan
dc.date.accessioned2024-08-04T20:38:04Z
dc.date.available2024-08-04T20:38:04Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe objective of this study was to analyze the clinical benefit of histopathologic analysis of appendectomy specimens from patients with an initial diagnosis of acute appendicitis. We retrospectively analyzed the demographic and histopathologic data of 1255 patients (712 males, 543 females; age range, 17-85 years) who underwent appendectomy to treat an initial diagnosis of acute appendicitis. Patients who underwent incidental appendectomy during other surgeries were excluded from the study. Histopathologic findings of the appendectomy specimens were used to confirm the initial diagnosis. Ninety-four percent of the appendectomy specimens were positive for appendicitis. Of those, 880 were phlegmonous appendicitis, 148 were gangrenous appendicitis with perforation, and the remaining 88 showed unusual histopathologic findings. In the 88 specimens with unusual pathology, fibrous obliteration was observed in 57 specimens, carcinoid tumor in 11, Encheliophis vermicularis parasite infection in 8, granulatomous inflammation in 6, appendiceal endometriosis in 2, and 1 specimen each showed mucocele, eosinophilic infiltration, Taenia saginata parasite infection, and appendicular diverticulitis. All carcinoid tumors were located in the distal appendix. Six of the 11 carcinoid tumors were defined by histopathology as involving tubular cells, and the other 5 as involving enterochromaffin cells. Six patients had muscularis propria invasion, 2 patients had submucosa invasion, 2 patients had mesoappendix invasion, and 1 patient had serosal invasion. All patients with tumors remained disease free during the follow-up (range, 127 months). We conclude that when the ratio of unusual pathologic findings for appendectomy specimens is considered, it is evident that all surgical specimens should be subjected to careful histologic examination.en_US
dc.identifier.doi10.9738/INTSURG-D-13-00098.1
dc.identifier.endpage362en_US
dc.identifier.issn0020-8868
dc.identifier.issue4en_US
dc.identifier.pmid24229023en_US
dc.identifier.scopus2-s2.0-84896537108en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage354en_US
dc.identifier.urihttps://doi.org/10.9738/INTSURG-D-13-00098.1
dc.identifier.urihttps://hdl.handle.net/11616/96367
dc.identifier.volume98en_US
dc.identifier.wosWOS:000327323100016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt College Of Surgeonsen_US
dc.relation.ispartofInternational Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAppendicitisen_US
dc.subjectCarcinoiden_US
dc.subjectOxyurisen_US
dc.subjectTaeniasisen_US
dc.subjectMucoceleen_US
dc.subjectEndometriosisen_US
dc.subjectAppendiceal neuromaen_US
dc.titleRoutine Histopathologic Examination of Appendectomy Specimens: Retrospective Analysis of 1255 Patientsen_US
dc.typeArticleen_US

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