A Nationwide Assessment of Turkish Society's Knowledge and Attitudes Toward Xenotransplantation

dc.contributor.authorAkbulut, Sami
dc.contributor.authorKucukakcali, Zeynep
dc.contributor.authorOzer, Ali
dc.contributor.authorColak, Cemil
dc.date.accessioned2026-04-04T13:33:19Z
dc.date.available2026-04-04T13:33:19Z
dc.date.issued2025
dc.departmentİnönü Üniversitesi
dc.description.abstractBackground: This study aimed to assess public perceptions, awareness, and attitudes toward xenotransplantation (XTx) and organ donation in Turkey by examining the influence of demographic, socioeconomic, and religious factors to identify barriers and facilitators to organ donation and XTx acceptance Methods: This cross-sectional survey was conducted with 10 650 participants, selected through stratified sampling to ensure national representation. Data collection was performed via Computer-Assisted Personal Interviewing (CAPI), with structured questionnaires designed to evaluate participants' perspectives on organ donation, XTx, and religious influences, and comparisons were made based on age groups, geographical region, sectarian affiliation, education level, belief categories, and economic status. ResultsOrgan donation rates were low across all demographic groups, with notable differences by geographical region, education level, income, age, and religious beliefs. The highest organ donation rate was in Central Anatolia (0.9%), while Southeastern Anatolia had the lowest (0.0%) (p = 0.014). Higher education (p = 0.001) and income levels (p = 0.01) correlated with greater organ donation support. Younger individuals (18-24 years) were less religiously observant, while older participants (65+) displayed the highest religious adherence (p = 0.022). Acceptance of XTx from halal animals was highest in the Aegean region (43.0%) (p = 0.001) and among participants with lower religious adherence (27.4%) (p = 0.004). Approval for XTx from non-halal animals was significantly lower, particularly among highly religious individuals (23.9%). Awareness of XTx-related studies was lowest among participants aged 65+ (9.4%) (p < 0.001) and highest among Maliki participants (27.3%). Conclusion: This study highlights the influence of demographic, socioeconomic, and religious factors on public attitudes toward organ donation and XTx in Turkey. These findings offer critical insights for policymakers and healthcare professionals to design culturally adaptive strategies that improve organ donation rates and foster XTx acceptance.
dc.description.sponsorshipInonu University Scientific Research Projects Coordination Unit; [TOA-2022-3151]
dc.description.sponsorshipThe authors thank the Inonu University Scientific Research Projects Coordination Unit (Project code: TOA-2022-3151) for the support. The authors would also like to thank all members of the coordination committee for their support. Also, english language and grammatical editing of this article was performed using ChatGPT.
dc.identifier.doi10.1111/xen.70048
dc.identifier.issn0908-665X
dc.identifier.issn1399-3089
dc.identifier.issue3
dc.identifier.orcid0000-0001-5406-098X
dc.identifier.pmid40375644
dc.identifier.scopus2-s2.0-105005275466
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1111/xen.70048
dc.identifier.urihttps://hdl.handle.net/11616/109076
dc.identifier.volume32
dc.identifier.wosWOS:001489733100001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofXenotransplantation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250329
dc.subjectdemographic influence
dc.subjectorgan donation
dc.subjectpublic perception
dc.subjectreligious beliefs
dc.subjectsocioeconomic factors
dc.subjectxenotransplantation
dc.titleA Nationwide Assessment of Turkish Society's Knowledge and Attitudes Toward Xenotransplantation
dc.typeArticle

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