Is Demodex folliculorum an aetiological factor in seborrhoeic dermatitis?

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dc.authoridKALAYCI, BULENT NURI/0000-0001-5838-8528
dc.authorwosidKALAYCI, BÜLENT/HKF-3285-2023
dc.contributor.authorKarincaoglu, Y.
dc.contributor.authorTepe, B.
dc.contributor.authorKalayci, B.
dc.contributor.authorAtambay, M.
dc.contributor.authorSeyhan, M.
dc.date.accessioned2024-08-04T20:32:13Z
dc.date.available2024-08-04T20:32:13Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. Seborrhoeic dermatitis (SD) is a common inflammatory skin disease for which no single cause has been found, although many factors have been implicated. The mite Demodex folliculorum (DF) is most commonly seen in the pilosebaceous unit in humans. SD is located in areas that are rich in sebaceous glands, which are also preferred by DF. Aims. To compare the number of DF parasites in patients with clinical SD and in healthy controls, and to investigate any possible relationship between the number of DF mites and the presence of SD. Methods. The study comprised 38 patients with SD and 38 healthy controls. Standard random and lesion-specific sampling was performed in the group of patients with SD, whereas standard random sampling only was performed for controls. Results. Demodex folliculorum sampling was positive in 19 patients (50%) and 5 controls (13.1%). Mean DF density was 8.16 +/- 10.1/cm(2) (range 0-40) and 1.03 +/- 2.17/cm(2) (1-7) in patient and control groups, respectively. The differences between groups for DF positivity and mean DF density were significant (P = 0.001 for each). DF was found in 13 lesional areas in the patient group, but in only 5 areas in the control group (P = 0.031). Conclusions. The number of DF mites was significantly higher in both lesional and nonlesional areas of patients with SD. This suggests that, when other aetiological causes are excluded, DF may have either direct or indirect role in the aetiology of SD.en_US
dc.identifier.doi10.1111/j.1365-2230.2009.03343.x
dc.identifier.endpageE520en_US
dc.identifier.issn0307-6938
dc.identifier.issue8en_US
dc.identifier.pmid19486039en_US
dc.identifier.scopus2-s2.0-72549116561en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageE516en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2009.03343.x
dc.identifier.urihttps://hdl.handle.net/11616/94932
dc.identifier.volume34en_US
dc.identifier.wosWOS:000272526800031en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwell Publishing, Incen_US
dc.relation.ispartofClinical and Experimental Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRosacea-Like Demodicidosisen_US
dc.subjectDandruffen_US
dc.subjectDensityen_US
dc.titleIs Demodex folliculorum an aetiological factor in seborrhoeic dermatitis?en_US
dc.typeArticleen_US

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