The new therapeutic option for female stress and stress-predominant mixed urinary incontinence: Periurethral hypertonic saline (10%) injection

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dc.authoridYILDIZ, Turan/0000-0001-5317-7537
dc.authoriddincer, murat/0000-0001-7110-4155
dc.authorwosidYILDIZ, Turan/ABI-1293-2020
dc.authorwosiddincer, murat/AAO-9621-2020
dc.contributor.authorTahtali, Ibrahim Nuvit
dc.contributor.authorYildiz, Turan
dc.contributor.authorDincer, Muhammed Murat
dc.date.accessioned2024-08-04T20:50:54Z
dc.date.available2024-08-04T20:50:54Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives We aimed to evaluate the safety and efficacy of periurethral hypertonic saline (10% NaCl) injection in the treatment of stress urinary incontinence (SUI) and stress-predominant mixed urinary incontinence (S-MUI) in women. Methods This was a prospective study conducted between January 2014 and April 2018 with 64 women (44 SUI and 21 S-MUI). Patients with SUI and S-MUI were evaluated using the Urinary Distress Inventory 6. Quality of life was evaluated with the Incontinence Quality of Life Scale and lower urinary tract symptoms of the women were evaluated with the International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Modules. Incontinence status and treatment success were assessed via the Stamey incontinence grade and pad test. Results The subjective success rate was 58.5%, and the objective success rate was 81.5%. The rate of reinjection was 21.5%, and the mean duration of reinjection was 8.92 months (3-19 months). Minor adverse effects were observed in 30.4% of the 79 injections. International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Modules and Incontinence Quality of Life Scale scores improved remarkably starting from the first month. Urinary Distress Inventory 6 scores in the S-MUI group also improved. Conclusions The results indicate that hypertonic saline injection is an effective and safe method in the treatment of SUI and S-MUI. Since hypertonic saline is a much cheaper and more accessible substance compared to bulking agents, it seems to be a viable alternative for urinary incontinence treatment in women.en_US
dc.identifier.doi10.1111/luts.12422
dc.identifier.endpage192en_US
dc.identifier.issn1757-5664
dc.identifier.issn1757-5672
dc.identifier.issue3en_US
dc.identifier.pmid34898031en_US
dc.identifier.scopus2-s2.0-85120968885en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage186en_US
dc.identifier.urihttps://doi.org/10.1111/luts.12422
dc.identifier.urihttps://hdl.handle.net/11616/100357
dc.identifier.volume14en_US
dc.identifier.wosWOS:000729312600001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofLuts-Lower Urinary Tract Symptomsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfemaleen_US
dc.subjecthypertonic saline solutionen_US
dc.subjectinjectionsen_US
dc.subjectstress urinary incontinenceen_US
dc.subjecttherapyen_US
dc.subjecturinary incontinenceen_US
dc.titleThe new therapeutic option for female stress and stress-predominant mixed urinary incontinence: Periurethral hypertonic saline (10%) injectionen_US
dc.typeArticleen_US

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