Kronik lösemili hastalarda eritrosit içi katalaz aktiviteleri
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Dosyalar
Tarih
1997
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Kronik lösemili hastalarda, eritrosit içi katalaz aktiviteleri, henüz tedaviye başlanmadan önce, Aebi'nin yöntemi kullanılarak tayin edildi. Her iki tip kronik lösemide de katalaz aktiviteleri, ortalamalara bakıldığında normal kontrol grubundan daha düşük olduğu halde, sadece kronik lenfositik lösemide istatistik olarak anlamlı düşüklük saptandı. Bu bulgular, katalazın eritrosit içi bir antioksidan enzim olarak kronik lösemilerde önemli bir role sahip olabileceğini düşündürmektedir.
Catalase (CAT) enzyme activities were measured in erythrocytes isolated from untreated patients with chronic leukemia, by using Aebi's method. In chronic lymphocytic leukemia, CAT activity was found to be significantly decreased and in chronic myeloid leukemia, it was found to be in normal ranges of activity although in both types of chronic leukemia, the activities were lower than the normal control group with respect to averages. These results suggest that catalase as an erythrocyte antioxidant enzyme may play an important role in chronic leukemias.
Catalase (CAT) enzyme activities were measured in erythrocytes isolated from untreated patients with chronic leukemia, by using Aebi's method. In chronic lymphocytic leukemia, CAT activity was found to be significantly decreased and in chronic myeloid leukemia, it was found to be in normal ranges of activity although in both types of chronic leukemia, the activities were lower than the normal control group with respect to averages. These results suggest that catalase as an erythrocyte antioxidant enzyme may play an important role in chronic leukemias.
Açıklama
[Journal of Turgut ÖzalMedical Center 1997;4(1):7-9]
Anahtar Kelimeler
Katalaz, Kronik lösemi, Eritrosit, Catalase, Chronic leukemia, Erythrocyte
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
1
Künye
Öztürk, İ. Ç.,Gözükara, Engin M.,Uysal, A.,(1997). Kronik lösemili hastalarda eritrosit içi katalaz aktiviteleri.Turgut Özal Tıp Merkezi Dergisi,4 (1). 7-9 ss.
