Simultaneous Electrochemical Detection of Estradiol and Testosterone Using Nickel Ferrite Oxide Doped Mesoporous Carbon Nanocomposite Modified Sensor

dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorTanrikut, Emrullah
dc.contributor.authorOzcan, Imren
dc.contributor.authorSel, Evren
dc.contributor.authorKoytepe, Sueleyman
dc.contributor.authorSavan, Ebru Kuyumcu
dc.date.accessioned2024-08-04T20:47:23Z
dc.date.available2024-08-04T20:47:23Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractEstradiol levels in women are related to lung, uterine (endometrial), ovarian and breast cancers, although the exact mechanism of cancer development is not fully understood. A new cost-effective sensor was fabricated by incorporating conductive NiFe2O4 metal oxide into the electrochemical sensitive platform of mesoporous carbon (MC) derived from cotton to measure estradiol determination by electrochemical methods. A new modified GCE/NiFe2O4-MC electrode, which exhibits electrocatalytic activities, was created by dropping NiFe2O4-MC onto the glassy carbon electrode (GCE) surface using the drop casting technique to detect the electroactive estradiol molecule. Estradiol was determined electrochemically by using the square wave voltammetry technique with a detection limit of 6.88 nM in 20.0-566 nM linear range in phosphate buffer solution at pH 7.4 with this novel modified GCE/NiFe2O4-MC electrode, that has the best electron transfer rate. The simultaneous determination of estradiol in the presence of testosterone was successfully performed in 0.1 M tetrabutylammonium tetrafluoroborate supportive electrolyte solution prepared in acetonitrile, an anhydrous medium. Real sample applications were carried out to prove the applicability and precision of the novelty-produced electrode. The amount of estradiol in tablet samples was obtained satisfactorily with high recovery values by standard addition method. (C) 2020 The Electrochemical Society (ECS). Published on behalf of ECS by IOP Publishing Limited.en_US
dc.description.sponsorshipResearch Fund Unit of nonu Universityen_US
dc.description.sponsorshipFinancial support from the Research Fund Unit of nonu University (grant no. FCD-2018-1274) is gratefully acknowledged.en_US
dc.identifier.doi10.1149/1945-7111/ab927f
dc.identifier.issn0013-4651
dc.identifier.issn1945-7111
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85086050308en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1149/1945-7111/ab927f
dc.identifier.urihttps://hdl.handle.net/11616/99335
dc.identifier.volume167en_US
dc.identifier.wosWOS:000537326200001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElectrochemical Soc Incen_US
dc.relation.ispartofJournal of The Electrochemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEstradiolen_US
dc.subjectTestosteroneen_US
dc.subjectNiFe2O4 Nanoparticlesen_US
dc.subjectMesoporous Carbon Sensoren_US
dc.titleSimultaneous Electrochemical Detection of Estradiol and Testosterone Using Nickel Ferrite Oxide Doped Mesoporous Carbon Nanocomposite Modified Sensoren_US
dc.typeArticleen_US

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