Naturally Occurring Cutaneous Anthrax: Antibiotic Treatment and Outcome

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dc.authoridÖzkurt, Zülal/0000-0001-5554-8768
dc.authoridKarahocagil, Mustafa Kasım/0000-0002-5171-7306
dc.authoridDoganay, Mehmet/0000-0003-3922-4901
dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authoridMetan, Gokhan/0000-0002-2676-4557
dc.authorwosidÖzkurt, Zülal/AAA-6833-2022
dc.authorwosidKarahocagil, Mustafa Kasım/JVZ-6523-2024
dc.authorwosidDoganay, Mehmet/G-4250-2019
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.contributor.authorKayabas, U.
dc.contributor.authorKarahocagil, M. K.
dc.contributor.authorOzkurt, Z.
dc.contributor.authorMetan, G.
dc.contributor.authorParlak, E.
dc.contributor.authorBayindir, Y.
dc.contributor.authorKalkan, A.
dc.date.accessioned2024-08-04T20:35:44Z
dc.date.available2024-08-04T20:35:44Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: Cutaneous anthrax (CA) is the most common clinical presentation in human anthrax, but the duration of antibiotic therapy in naturally occurring CA is controversial. The aim of this study was to compare the clinical outcomes of patients receiving antibiotic treatment for either 3-5 days (group 1) or 7-10 days (group 2) in uncomplicated CA. Methods: A total of 66 patients were enrolled; 29 (44%) in group 1 and 37 (56%) in group 2. Infections were classified as mild (n = 22, 33%) or severe (n = 44, 67%) CA. Results: There were no significant differences between the groups in symptom resolution time, fever clearance time, healing of lesions, development and healing of eschars, requirement for surgical intervention or the development of complications. Both edema resolution time and duration of hospital stay were longer in group 2. There were no therapeutic failures, relapses or deaths in either group. Steroid therapy was used in 32% of patients with severe CA, but a beneficial effect on resolution of edema was not demonstrated. Conclusions: These results suggest that short-course antibiotic therapy is as effective as standard-duration therapy in uncomplicated CA and that steroid therapy may not be effective. Copyright (C) 2012 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000335593
dc.identifier.endpage43en_US
dc.identifier.issn0009-3157
dc.identifier.issn1421-9794
dc.identifier.issue1en_US
dc.identifier.pmid22343361en_US
dc.identifier.scopus2-s2.0-84856878949en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage34en_US
dc.identifier.urihttps://doi.org/10.1159/000335593
dc.identifier.urihttps://hdl.handle.net/11616/95562
dc.identifier.volume58en_US
dc.identifier.wosWOS:000301625200005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofChemotherapyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnthraxen_US
dc.subjectAntimicrobial therapyen_US
dc.subjectBacillus anthracisen_US
dc.subjectBacterial infectionen_US
dc.subjectCutaneous anthraxen_US
dc.subjectGram-positive bacteriaen_US
dc.titleNaturally Occurring Cutaneous Anthrax: Antibiotic Treatment and Outcomeen_US
dc.typeArticleen_US

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