The Turkish experience with therapeutic plasma exchange: A national survey

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dc.authoridDemircioğlu, Sinan/0000-0003-1277-5105
dc.authoridDogu, Mehmet Hilmi/0000-0001-7237-2637
dc.authoridAfacan Öztürk, Hacer Berna/0000-0001-9386-7604
dc.authoridgulturk, emine/0000-0003-2836-6162
dc.authoridSevindik, Omur Gokmen/0000-0001-9636-4113
dc.authoridBERBER, Ilhami/0000-0003-3312-8476
dc.authoridErkurt, Mehmet Ali/0000-0002-3285-417X
dc.authorwosidDemircioğlu, Sinan/AAF-9901-2020
dc.authorwosidDogu, Mehmet Hilmi/W-2255-2017
dc.authorwosidAfacan Öztürk, Hacer Berna/AAN-1699-2020
dc.authorwosidTeke, Hava Üsküdar/ABH-8319-2020
dc.authorwosidAkgun Cagliyan, Gulsum/AAA-5330-2022
dc.authorwosidgulturk, emine/ABB-5387-2020
dc.authorwosidUlas, Turgay TU/A-6050-2018
dc.contributor.authorKorkmaz, Serdal
dc.contributor.authorMedeni, Serife Solmaz
dc.contributor.authorDemirkan, Fatih
dc.contributor.authorBesisik, Sevgi Kalayoglu
dc.contributor.authorDadin, Senem Altay
dc.contributor.authorCagliyan, Gulsum Akgun
dc.contributor.authorHacioglu, Sibel Kabukcu
dc.date.accessioned2024-08-04T20:45:53Z
dc.date.available2024-08-04T20:45:53Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTherapeutic plasma exchange (TPE) is used to treat more than 60 diseases worldwide and has drawn growing interest. Little is known about the current situation of TPE activity in Turkey, so we developed a survey to obtain information about this timely topic. We collected data on TPE from 28 apheresis units throughout Turkey. We performed a total of 24,912 TPE procedures with 3203 patients over the past decade. Twenty years ago, the majority of procedures were performed for neurological and hematological disorders, and today, most TPE procedures are done for the same reasons. The only historical change has been an increase in TPE procedures in renal conditions. Currently, renal conditions were more frequently an indication for TPE than rheumatic conditions. Fresh frozen plasma was the most frequently used replacement fluid, followed by 5% albumin, used in 57.9% and 34.6% of procedures, respectively. The most frequently used anticoagulants in TPE were ACD-A and heparin/ACD-A, used with 1671 (52.2%) and 1164 (36.4%) patients, respectively. The frequency of adverse events (AEs) was 12.6%. The most common AEs were hypocalcemia-related symptoms, hypotension, and urticaria. We encountered no severe AEs that led to severe morbidity and mortality. Overall, more than two thirds of the patients showed improvement in the underlying disease. Here, we report on a nationwide survey on TPE activity in Turkey. We conclude that there has been a great increase in apheresis science, and the number of TPE procedures conducted in Turkey has increased steadily over time. Finally, we would like to point out that our past experiences and published international guidelines were the most important tools in gaining expertise regarding TPE.en_US
dc.identifier.doi10.1016/j.transci.2019.04.015
dc.identifier.endpage292en_US
dc.identifier.issn1473-0502
dc.identifier.issue3en_US
dc.identifier.pmid31036516en_US
dc.identifier.scopus2-s2.0-85064687488en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage287en_US
dc.identifier.urihttps://doi.org/10.1016/j.transci.2019.04.015
dc.identifier.urihttps://hdl.handle.net/11616/98768
dc.identifier.volume58en_US
dc.identifier.wosWOS:000473249400014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTransfusion and Apheresis Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTurkish experienceen_US
dc.subjectTherapeutic plasma exchangeen_US
dc.subjectNational surveyen_US
dc.titleThe Turkish experience with therapeutic plasma exchange: A national surveyen_US
dc.typeArticleen_US

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