Simultaneous determination of levodopa and benserazide using poly(3-methylthiophene) and a multi-walled carbon nanotube sensor

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dc.authoridERDOGDU, GAMZE/0000-0002-8114-6946
dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidERDOGDU, GAMZE/ABG-7776-2020
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorKuyumcu Savan, Ebru
dc.contributor.authorErdoadu, Gamze
dc.date.accessioned2024-08-04T20:43:02Z
dc.date.available2024-08-04T20:43:02Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractRapid, reliable, reproducible, and repeatable modified sensor designs have been developed to distinguish the binary mixture of levodopa and benserazide in the presence of ascorbic acid using voltammetric techniques. Sixteen designed sensors were prepared by dropwise of different concentrations and quantities of multi-walled carbon nanotube (MWCNT) dispersions to bare glassy carbon electrode (GCE) surface and also the bottom and the top of the poly(3-methylthiophene) films. The best simultaneous determination was accomplished with the sensor dropped 20 mu L of 1.0% MWCNT to GCE. Under optimum conditions, the electrocatalytic oxidation peak currents of levodopa and benserazide showed linear dynamic range, good stability, and sensitivity with detection limit of 10.3 and 32.5 mu mol L-1, respectively. The proposed method has been successfully applied for the determination of levodopa and benserazide in urine samples and pharmaceutical preparations, demonstrating the feasibility and reliability.en_US
dc.description.sponsorshipResearch Fund Unit of Inonu University [APYB:2013-54]en_US
dc.description.sponsorshipThis study was financially supported by the Research Fund Unit of Inonu University (grant no. APYB:2013-54).en_US
dc.identifier.doi10.1007/s10008-017-3549-8
dc.identifier.endpage2217en_US
dc.identifier.issn1432-8488
dc.identifier.issn1433-0768
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-85015938440en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2209en_US
dc.identifier.urihttps://doi.org/10.1007/s10008-017-3549-8
dc.identifier.urihttps://hdl.handle.net/11616/97747
dc.identifier.volume21en_US
dc.identifier.wosWOS:000406177400006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Solid State Electrochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLevodopaen_US
dc.subjectBenserazideen_US
dc.subject3-methylthiopheneen_US
dc.subjectMulti-walled carbon nanotubeen_US
dc.subjectVoltammetryen_US
dc.titleSimultaneous determination of levodopa and benserazide using poly(3-methylthiophene) and a multi-walled carbon nanotube sensoren_US
dc.typeArticleen_US

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