Characterization of the Biological Activity and Phenolics in Achillea lycaonica

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dc.authoridARABACI, Turan/0000-0003-3869-4557
dc.authoridTaşkın, Duygu/0000-0002-5279-0900
dc.authoridDikpınar, Tuğçe/0000-0002-3994-3888
dc.authoridtaskin, turgut/0000-0001-8475-6478
dc.authoridSuzgec Selcuk, Sevda/0000-0002-1552-7521
dc.authorwosidARABACI, Turan/AAQ-3885-2020
dc.authorwosidTaşkın, Duygu/HIR-3042-2022
dc.authorwosidDikpınar, Tuğçe/HKE-3551-2023
dc.authorwosidtaskin, turgut/AAE-4680-2020
dc.authorwosidSelcuk, Sevda Suzgec/AAD-7905-2020
dc.contributor.authorTaskin, Turgut
dc.contributor.authorTaskin, Duygu
dc.contributor.authorRayaman, Erkan
dc.contributor.authorDikpinar, Tugce
dc.contributor.authorSuzgec-Selcuk, Sevda
dc.contributor.authorArabaci, Turan
dc.date.accessioned2024-08-04T20:44:05Z
dc.date.available2024-08-04T20:44:05Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe purpose of this study was to comparatively evaluate for the first time the antioxidant, antimicrobial, and antiurease effects of A. lycaonica extracts obtained using three extraction methods and five solvents followed by identification of the phenolic compounds obtained by Soxhlet extraction with ethyl acetate and maceration with chloroform that showed the highest total phenolic and flavonoid contents with antioxidant and antiurease activity. The phenolic compounds were identified to be chlorogenic acid, caffeic acid, rutin, dicaffeoylquinic acid, salicylic acid, luteolin, quercetin, naringenin, apigenin, and 8-hydroxy- salvigenin. Among the solvent extraction procedures, Soxhlet approach was found to have higher recoveries than other approaches. The results of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assays showed that the 1: 1 ethanol-water Soxhlet, ethanol ultrasonic bath, and ethyl acetate Soxhlet extraction methods had the highest DPPH antioxidant activities. The ethyl acetate Soxhlet extraction method showed the highest 2, 2'-azino-bis(3-ethylbenzthiazoline- 6-sulfonic acid) diammonium salt (ABTS) and ferric reducing antioxidant power (FRAP) antioxidant activity. In addition, the chloroform maceration extraction method exhibited the highest antiurease activity. Therefore, 1: 1 Soxhlet ethanol-water, ultrasonic bath ethanol, and Soxhlet ethyl acetate extracts may be used in medicine and food production as natural antioxidant sources. In addition, maceration with chloroform may provide a potential antiurease agent.en_US
dc.description.sponsorshipMarmara University Scientific Research Committee [SAG-K-200716-0361]en_US
dc.description.sponsorshipThis research was financially supported by the Marmara University Scientific Research Committee (Project No: SAG-K-200716-0361).en_US
dc.identifier.doi10.1080/00032719.2017.1318140
dc.identifier.endpage48en_US
dc.identifier.issn0003-2719
dc.identifier.issn1532-236X
dc.identifier.issue1-2en_US
dc.identifier.scopus2-s2.0-85032209395en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage33en_US
dc.identifier.urihttps://doi.org/10.1080/00032719.2017.1318140
dc.identifier.urihttps://hdl.handle.net/11616/98006
dc.identifier.volume51en_US
dc.identifier.wosWOS:000416519900004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofAnalytical Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectA. lycaonicaen_US
dc.subjectantimicrobialen_US
dc.subjectantioxidanten_US
dc.subjectantiureaseen_US
dc.subjectliquid chromatography with quadrupole time-of-flight mass spectrometry (Q-TOF LC/MS)en_US
dc.titleCharacterization of the Biological Activity and Phenolics in Achillea lycaonicaen_US
dc.typeArticleen_US

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