Predictive Factors of Postoperative Pancreatic Fistula in Geriatric Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancy

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dc.authoridCeylan, Cengiz/0000-0003-3471-8726
dc.authorwosidCeylan, Cengiz/AAC-7461-2022
dc.contributor.authorCeylan, Cengiz
dc.contributor.authorKocaaslan, Huseyin
dc.contributor.authorBaran, Necip Tolga
dc.contributor.authorKulus, Mehmet
dc.contributor.authorSaglam, Kutay
dc.contributor.authorAydin, Cemalettin
dc.date.accessioned2024-08-04T20:54:56Z
dc.date.available2024-08-04T20:54:56Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To identify predictive factors associated with the occurrence of postoperative pancreatic fistula (POPF) following pancreato-duodenectomy (PD) in an increasingly geriatric population.Study Design: Observational study.Place and Duration of the Study: Department of General Surgery, Inonu University, Malatya, Turkey, from January 2010 to April 2022.Methodology: Demographic and clinicopathological data of 74 geriatric patients who underwent PD for periampullary tumours in the clinic at Inonu University were retrieved from the patient database. POPF was defined and categorised based on the guidelines established by the International Study Group for Pancreatic Surgery (ISGPS). The patients were stratified into two cohorts of POPF and no POPF. Univariate and multivariate analyses were conducted to compare variables between the two groups.Results: The median age of the patient population was 72 (65-92) years, and 51 (68.9%) individuals were male. Among the 74 patients, 35 (47.3%) experienced POPF. In the multivariate analysis, hypertension (HT, p=0.012), Wirsung diameter <3.5 mm (p<0.01), and pancreaticojejunostomy (PJ, p=0.022) emerged as independent risk factors for POPF.Conclusion: In the context of geriatric patients undergoing PD, HT, intraoperative wirsung diameter <3.5 mm, and PJ were identified as independent risk factors for POPF. These findings can guide the adoption of safer techniques in preoperative and intraoperative evaluations, as well as in postoperative follow-ups of patients presenting with these risk factors.en_US
dc.identifier.doi10.29271/jcpsp.2023.12.1439
dc.identifier.endpage1444en_US
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue12en_US
dc.identifier.pmid38062603en_US
dc.identifier.scopus2-s2.0-85179643474en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1439en_US
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2023.12.1439
dc.identifier.urihttps://hdl.handle.net/11616/101722
dc.identifier.volume33en_US
dc.identifier.wosWOS:001117798400016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherColl Physicians & Surgeons Pakistanen_US
dc.relation.ispartofJcpsp-Journal of The College of Physicians and Surgeons Pakistanen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElderlyen_US
dc.subjectAnastomotic leakageen_US
dc.subjectPredictive factoren_US
dc.subjectPostoperative pancreatic fistulaen_US
dc.subjectPancreatoduodenectomyen_US
dc.titlePredictive Factors of Postoperative Pancreatic Fistula in Geriatric Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancyen_US
dc.typeArticleen_US

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