Serological Diagnosis of Autoimmune Blistering Diseases
Küçük Resim Yok
Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Galenos Yayincilik
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Autoimmune blistering diseases are a rare diseases, characterized by development of autoantibodies against the structural proteins of the epidermis or dermoepidermal junction, and blisters and erosions on skin and/or mucous membranes clinically. Clinical features are important guiding findings for suspicious of this group of diseases. The diagnosis is achieved by the evaluation together of clinical features, histological and immunological findings. The gold standard in the diagnosis of this group diseases are demonstration of tissue bound and/or circulating autoantibodies. Methods for this purpose are; direct and indirect immunofluorescence, Enzyme Linked Immunosorbent Assay (ELISA), immunoprecipitation and immunoblotting. The aim of this paper is to review serological diagnostic methods in the diagnosis of autoimmune bullous diseases and to present developments in recent years.
Açıklama
Anahtar Kelimeler
Autoimmune blistering diseases, diagnosis, immunofluorescence findings, biochip, Enzyme Linked Immunosorbent Assay
Kaynak
Turk Dermatoloji Dergisi-Turkish Journal of Dermatology
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
10
Sayı
1
