Detection of extended spectrum beta-lactamases and antibiotic susceptibilities of Klebsiella pneumoniae strains
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
One hundred Klebsiella pneumoniae strains isolated from various clinical specimens were investigated for the presence of extended spectrum beta-lactamases (ESBL) and the antimicrobial susceptibility patterns. The ESBL production was detected in 44% of strains isolated from inpatients and 14% of strains isolated from outpatients. The antimicrobial susceptibility rates of the total 100 strains and ESBL positive 58 strains were found to be as follows respectively: Cephalotin and cefuroxime 40% and 0%, cefoxitin 78% and 100%, ceftazidime 48% and 20%, cefotaxime 56% and 20%, ceftriaksone 52% and 18%, gentamicin 66% and 40%, amikacin 70% and 65%, ciprofloxacin 88% and 90%, imipenem 80% and 90%, meropenem 100% and 100%, aztreonam 50% and 30%, amoxicillin-clavulonic acid 28% and 10%, and trimethoprimsulphametoxazole 72% and 40 percent. The results indicated that ciprofloxacin, imipenem and meropenem might be used in the therapy of infections due to K. pneumoniae.
Açıklama
Anahtar Kelimeler
Antimicrobial susceptibility, Extended spectrum beta-lactamase, Klebsiella pneumoniae
Kaynak
Mikrobiyoloji Bulteni
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
35
Sayı
2