Comparison of Antiaging Effects on Rat Skin of Cog Thread and Poly-L-Lactic Acid Thread

Basit Öğe Kaydı
dc.authoridGül, Mehmet/0000-0002-1374-0783
dc.authoridGozukara Bag, Harika Gozde/0000-0003-1208-4072
dc.authorwosidSarac, Gulbahar/ABF-3119-2020
dc.authorwosidGül, Mehmet/ABI-6336-2020
dc.authorwosidGozukara Bag, Harika Gozde/ABG-7588-2020
dc.contributor.authorKapicioglu, Yelda
dc.contributor.authorGul, Mehmet
dc.contributor.authorSarac, Gulbahar
dc.contributor.authorYigitcan, Birgul
dc.contributor.authorGozukara, Harika
dc.date.accessioned2024-08-04T20:45:50Z
dc.date.available2024-08-04T20:45:50Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND Polydioxanone Cog thread and poly-L-lactic acid (PLLA) thread have been used clinically for lifting and antiaging purposes. However, the histological changes in tissue and the efficacy of these 2 different types of thread have not been compared. OBJECTIVE This study used hematoxylin and eosin (H&E) staining, Masson's trichrome staining, and electron microscopy (EM) to compare the results associated with the use of Cog thread and PLLA thread in rat skin. METHODS Thirty female rats were divided into 3 groups of 10 rats each: a control group; a Cog group; and a PLLA group. Biopsy specimens obtained at 1, 3, and 6 months were examined using H&E, MT, and EM. RESULTS Although significant increases were observed in dermal thickness and the numbers of fibroblasts in the PLLA group compared with the control group within the first month (p: .019), there were no significant differences between the Cog and control groups during this period (p: .245). Dermal thickness (p: .002) and numbers of fibroblasts (p: .001) were similar in samples obtained from the PLLA and Cog groups at 3 and 6 months, and both groups showed significantly improved outcomes compared with the control group. CONCLUSION Poly-L-lactic acid and Cog sutures were effective in facial rejuvenation; both increased dermis thickness and stimulated collagen production.en_US
dc.description.sponsorshipInonu University Scientific Research Projects Uniten_US
dc.description.sponsorshipSupported by the Inonu University Scientific Research Projects Unit. This study was presented as a poster at the 26th European Academy of Dermatology and Venereology Congress; September 13-17, 2017; Geneva, Switzerland. The authors have indicated no significant interest with commercial supporters.en_US
dc.identifier.doi10.1097/DSS.0000000000001717
dc.identifier.endpage445en_US
dc.identifier.issn1076-0512
dc.identifier.issn1524-4725
dc.identifier.issue3en_US
dc.identifier.pmid30608294en_US
dc.identifier.scopus2-s2.0-85062693593en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage438en_US
dc.identifier.urihttps://doi.org/10.1097/DSS.0000000000001717
dc.identifier.urihttps://hdl.handle.net/11616/98715
dc.identifier.volume45en_US
dc.identifier.wosWOS:000462415600014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofDermatologic Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolydioxanoneen_US
dc.titleComparison of Antiaging Effects on Rat Skin of Cog Thread and Poly-L-Lactic Acid Threaden_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu