Antioxidative role of selenium against the toxic effect of heavy metals (Cd+2 Cr+3 on liver of rainbow trout (Oncorhynchus mykiss Walbaum 1792)

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dc.authoridYılmaz, İsmet/0000-0002-7204-1050
dc.authoriderdogan, kenan/0000-0003-0447-1582;
dc.authorwosidYılmaz, İsmet/P-9976-2015
dc.authorwosidYılmaz, ismet/AAG-8946-2019
dc.authorwosiderdogan, kenan/KFB-5801-2024
dc.authorwosidÖzdemir, İlknur/AAA-6216-2021
dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorOrun, Ibrahim
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorErdogan, Kenan
dc.contributor.authorAlkan, Aysel
dc.contributor.authorYilmaz, Ismet
dc.date.accessioned2024-08-04T20:30:56Z
dc.date.available2024-08-04T20:30:56Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe main purpose of this study is to discuss the effect of Cd+2, Cr+3 and Se metals on biochemical parameters in liver tissue of Oncorhynchus mykiss. The rainbow trout were exposed to heavy metal stress ( Cd+2, Cr+3) at 2 ppm dosage. The present study was undertaken to determine the protective effect of selenium treatment at the same dosage ( 2 ppm) on some biochemical parameters. The activity of catalase ( CAT), glutathione peroxidase ( GSH-Px), superoxide dismutase ( SOD) and the changes in levels of malondialdehyde ( MDA) from biochemical parameters were determined in liver tissue of the fish groups exposed to heavy metals, especially for the selenium-applied groups. Results of this study showed that the activities of CAT, GSH-Px and SOD in the tissues of fish exposed to the stress of Cd+2 and Cr+3 were significantly lower than the control groups ( P < 0.05). Meanwhile, the closer values to the control groups were obtained in selenium-added groups ( Cr+3 + Se+4, Cd+2 + Se+4). For the level of MDA, the last production of lipid peroxidation showed increases ( P < 0.05) in the groups exposed to the metal stress, whereas significant decreases were obtained in selenium-applied groups. The result of the statistical evaluation showed that the negative effects occurring in the biochemical parameters of the applied groups exposed to the toxicity of heavy metal were significantly eliminated ( P < 0.05) as a result of selenium treatment.en_US
dc.identifier.doi10.1007/s10695-007-9179-9
dc.identifier.endpage222en_US
dc.identifier.issn0920-1742
dc.identifier.issn1573-5168
dc.identifier.issue3en_US
dc.identifier.pmid18665459en_US
dc.identifier.scopus2-s2.0-48649087993en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://doi.org/10.1007/s10695-007-9179-9
dc.identifier.urihttps://hdl.handle.net/11616/94613
dc.identifier.volume34en_US
dc.identifier.wosWOS:000258086500004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofFish Physiology and Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant enzymeen_US
dc.subjectHeavy metal (Cd+2, Cr+3)en_US
dc.subjectLipid peroxidationen_US
dc.subjectLiveren_US
dc.subjectOncorhynchus mykissen_US
dc.subjectOxidative stressen_US
dc.subjectSeleniumen_US
dc.titleAntioxidative role of selenium against the toxic effect of heavy metals (Cd+2 Cr+3 on liver of rainbow trout (Oncorhynchus mykiss Walbaum 1792)en_US
dc.typeArticleen_US

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