Mean Platelet Volume in Neonatal Sepsis

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dc.authoridOGUZ, SUNA SERIFE/0000-0002-1870-0983
dc.authoridOncel, Mehmet Yekta/0000-0003-0760-0773
dc.authoridERDEVE, OMER/0000-0002-3193-0812
dc.authoridCanpolat, Fuat Emre/0000-0001-9307-3003
dc.authorwosidOGUZ, SUNA SERIFE/GWZ-7382-2022
dc.authorwosidUras, Nurdan/AAR-5383-2020
dc.authorwosidOncel, Mehmet Yekta/L-5664-2013
dc.authorwosidERDEVE, Omer/W-1480-2017
dc.authorwosidCanpolat, Fuat Emre/P-3992-2018
dc.contributor.authorOncel, Mehmet Yekta
dc.contributor.authorOzdemir, Ramazan
dc.contributor.authorYurttutan, Sadik
dc.contributor.authorCanpolat, Fuat Emre
dc.contributor.authorErdeve, Omer
dc.contributor.authorOguz, Serife Suna
dc.contributor.authorUras, Nurdan
dc.date.accessioned2024-08-04T20:36:12Z
dc.date.available2024-08-04T20:36:12Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground The aim of this study was to investigate any changes in mean platelet volume (MPV) in patients with neonatal sepsis (NS). Methods Subjects were stratified into two groups: proven sepsis (Group 1a) and clinical sepsis (Group 1b). The control group (Group 2) consisted of healthy newborns matched for gestational age and birth weight. Results A total of 100 patients with NS (35 with proven sepsis and 65 with clinical sepsis) and 50 healthy controls were enrolled. A comparison of markers of sepsis obtained at baseline revealed white blood cell count (WBC), C-reactive protein (CRP), interleukin-6 (IL-6), and MPV levels to be significantly higher in newborns with sepsis compared to healthy controls (P = 0.01, <0.001, <0.001, and 0.001, respectively). Mean baseline serum levels of CRP and MPV were significantly higher in Group 1a compared to Group 1b (P = 0.003, P = 0.007, respectively), whereas the difference between group with regards to baseline serum levels of IL-6 and platelet count was statistically insignificant (P = 0.14, P = 0.28, respectively). Conclusion This is the first study to demonstrate a statistically significant difference with regard to baseline MPV values between patients with sepsis (proven or clinical) and healthy controls. J. Clin. Lab. Anal. 26:493-496, 2012. (C) 2012 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/jcla.21552
dc.identifier.endpage496en_US
dc.identifier.issn0887-8013
dc.identifier.issn1098-2825
dc.identifier.issue6en_US
dc.identifier.pmid23143634en_US
dc.identifier.scopus2-s2.0-84869045288en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage493en_US
dc.identifier.urihttps://doi.org/10.1002/jcla.21552
dc.identifier.urihttps://hdl.handle.net/11616/95852
dc.identifier.volume26en_US
dc.identifier.wosWOS:000310973200013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Clinical Laboratory Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectmean platelet volumeen_US
dc.subjectneonatal sepsisen_US
dc.subjectC-reactive proteinen_US
dc.subjectinterleukin-6en_US
dc.titleMean Platelet Volume in Neonatal Sepsisen_US
dc.typeArticleen_US

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