New-Onset Atrial Fibrillation Following Isolated Coronary Artery Bypass Grafting: Is Pulmonary Hypertension a Risk Factor?

Küçük Resim Yok

Tarih

2025

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Soc Brasil Cirurgia Cardiovasc

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Introduction: This study aimed to clarify whether pulmonary hypertension is a risk factor for postoperative new-onset atrial fibrillation (NOAF) following isolated coronary artery bypass grafting (CABG). Methods: Data of 4,782 patients were retrospectively examined from clinical database, and data of isolated CABG performed patients (n = 854) with preoperative echocardiography including pulmonary artery pressure (PAP) measurement were enrolled in study. While 115 patients had post-CABG NOAF (atrial fibrillation [AF] group), 739 did not have AF (non-AF group). Demographic, clinical, and treatment-related parameters were compared between groups, and independent clinical predictors of NOAF were identified by multivariate analysis. Results: Patients of AF group were significantly older and had higher European System for Cardiac Operative Risk Evaluation (EuroSCORE) points, significantly elevated mean systolic PAP, and more pulmonary hypertension. Multivariate regression analysis revealed that mean systolic PAP (odds ratio [OR]: 1.027, 95% confidence interval [CI]: 1.006-1.048) and pulmonary hypertension (>= 30 mmHg; OR: 1.659, 95% CI: 1.093-2.518) were independent risk factors for post-CABG NOAF. Chronic obstructive pulmonary disease (COPD) (OR: 2.033, 95% CI: 1.265-3.268) and mean duration of ventilation support (OR: 1.059, 95% CI: 1.017-1.104) were additionally determined as risk factors for post-CABG NOAF. Conclusion: This study identified patients'age, high EuroSCORE points, presence of COPD, prolonged ventilation support, and increased PAP as predictors of post-CABG NOAF. Understanding the risk factors will provide better guidance in preventing this complication and its potential consequences. Prospective randomized controlled trials are required to further validate these findings and provide more robust evidence.

Açıklama

Anahtar Kelimeler

Surgery

Kaynak

Brazilian Journal of Cardiovascular Surgery

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

40

Sayı

5

Künye