Celiac disease in children with urolithiasis

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dc.authoridgürgöze, metin kaya/0000-0003-0645-8170;
dc.authorwosidgürgöze, metin kaya/W-6665-2018
dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.contributor.authorMenekse, Engin
dc.contributor.authorSelimoglu, Mukadder Ayse
dc.contributor.authorTemel, Ismail
dc.contributor.authorTabel, Yilmaz
dc.contributor.authorGurgoze, Metin
dc.date.accessioned2024-08-04T20:37:25Z
dc.date.available2024-08-04T20:37:25Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThere are a few studies suggesting a relationship between celiac disease (CD) and kidney disease, but no study has investigated CD in patients with urolithiasis. In this study, we aimed to determine the prevalence of CD in infants and children with urolithiasis. One hundred and eighty-seven infants and children (4 months-17 years) with urolithiasis, and 278 age- and sex-matched healthy children were included. CD was screened using tissue transglutaminase (tTG) immunoglobulin (Ig) A. Seropositive cases, whose parents gave consent, underwent upper gastrointestinal system endoscopy for duodenal biopsy. Seven (3.7%) among those with urolithiasis and one (0.3%) among controls were positive for tTG IgA (p=0.008). Six of the urolithiasis group and one from the control group underwent upper gastrointestinal endoscopy. Intestinal biopsy revealed Marsh-Oberhuber type 1 intestinal lesions in two children. The other five had normal histology. Biopsy-proven CD was detected in two (1%) children with urolithiasis. The prevalence of biopsy-proven CD among all cases was 0.4%. When children were evaluated with respect to age factor, it was found that seropositivity in children younger and older than two years was not different (4% vs. 3.6%; p=0.880). In this first study investigating CD prevalence in children with urolithiasis, we found a higher seropositivity for CD in children with urolithiasis compared to controls, but in terms of biopsy-proven CD, no difference was found.en_US
dc.description.sponsorshipInonu University Scientific Research Projects Unit [2009/29]en_US
dc.description.sponsorshipThis study was funded by Inonu University Scientific Research Projects Unit (No: 2009/29).en_US
dc.identifier.endpage386en_US
dc.identifier.issn0041-4301
dc.identifier.issue4en_US
dc.identifier.pmid23692719en_US
dc.identifier.scopus2-s2.0-84873874884en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage382en_US
dc.identifier.urihttps://hdl.handle.net/11616/95954
dc.identifier.volume54en_US
dc.identifier.wosWOS:000209048300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectceliac diseaseen_US
dc.subjectchildrenen_US
dc.subjecturolithiasisen_US
dc.titleCeliac disease in children with urolithiasisen_US
dc.typeArticleen_US

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