Antibacterial and antifungal activities of complexes of ruthenium (II)
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Georg Thieme Verlag Kg
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Twenty ruthenium (IT) complexes (1-5) were evaluated for their in vitro antibacterial and antifungal activity against Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans and Candida tropicalis. Compounds Id! le, Ih, ii and Ij showed more pronounced antimicrobial activity against Gram-positive bacteria and fungi as compared to the nitrogen donor ruthenium complexes; hydrophobic substituents were significantly mon effective. None of the compounds 1-5 exhibited antimicrobial activity against the Gram-negative strains Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853) with the concentrations ranging between 17.5 and 800 mu g/ml.
Açıklama
Anahtar Kelimeler
benzimidazole, carbene complexes, imidazoline, ruthenium(II) complexes, antibacterial activity, antifungal activity, in vitro studies tetrahydropyridine, vinylpyridine
Kaynak
Arzneimittelforschung-Drug Research
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
49
Sayı
6
