Blood Glucose Regulation During Living-Donor Liver Transplant Surgery

Basit Öğe Kaydı
dc.authoridGedik, Ender/0000-0002-7175-207X
dc.authoridToprak, Hüseyin İlksen/0000-0001-9293-8116
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridŞahin, Taylan/0000-0002-9888-6625
dc.authoridOZGUL, Ulku/0000-0003-3738-1751
dc.authoridKOCA, ERDINC/0000-0002-6691-6711
dc.authorwosidGedik, Ender/ABI-2971-2020
dc.authorwosidToprak, Hüseyin İlksen/AAN-4023-2020
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidŞahin, Taylan/AAT-4038-2020
dc.authorwosidsahin, taylan/IWD-9406-2023
dc.authorwosidOZGUL, Ulku/ABI-6823-2020
dc.authorwosidKOCA, ERDINC/GSJ-0735-2022
dc.contributor.authorGedik, Ender
dc.contributor.authorToprak, Huseyin Ilksen
dc.contributor.authorKoca, Erdinc
dc.contributor.authorSahin, Taylan
dc.contributor.authorOzgul, Ulku
dc.contributor.authorErsoy, Mehmet Ozcan
dc.date.accessioned2024-08-04T20:41:08Z
dc.date.available2024-08-04T20:41:08Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description14th Congress of the Middle-East-Society-for-Organ-Transplantation / 5th Middle East Transplant Games -- SEP 10-13, 2014 -- Istanbul, TURKEYen_US
dc.description.abstractObjectives: The goal of this study was to compare the effects of 2 different regimens on blood glucose levels of living-donor liver transplant. Materials and Methods: The study participants were randomly allocated to the dextrose in water plus insulin infusion group (group 1, n = 60) or the dextrose in water infusion group (group 2, n = 60) using a sealed envelope technique. Blood glucose levels were measured 3 times during each phase. When the blood glucose level of a patient exceeded the target level, extra insulin was administered via a different intravenous route. The following patient and procedural characteristics were recorded: age, sex, height, weight, body mass index, end-stage liver disease, Model for End-Stage Liver Disease score, total anesthesia time, total surgical time, and number of patients who received an extra bolus of insulin. The following laboratory data were measured pre- and postoperatively: hemoglobin, hematocrit, platelet count, prothrombin time, international normalized ratio, potassium, creatinine, total bilirubin, and albumin. Results: No hypoglycemia was noted. The recipients exhibited statistically significant differences in blood glucose levels during the dissection and neohepatic phases. Blood glucose levels at every time point were significantly different compared with the first dissection time point in group 1. Excluding the first and second anhepatic time points, blood glucose levels were significantly different as compared with the first dissection time point in group 2 (P < .05). Conclusions: We concluded that dextrose with water infusion alone may be more effective and result in safer blood glucose levels as compared with dextrose with water plus insulin infusion for living-donor liver transplant recipients. Exogenous continuous insulin administration may induce hyperglycemic attacks, especially during the neohepatic phase of living-donor liver transplant surgery. Further prospective studies that include homogeneous patient subgroups and diabetic recipients are needed to support the use of dextrose plus water infusion without insulin.en_US
dc.identifier.doi10.6002/ect.mesot2014.P137
dc.identifier.endpage300en_US
dc.identifier.issn1304-0855
dc.identifier.pmid25894177en_US
dc.identifier.scopus2-s2.0-84939813489en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage294en_US
dc.identifier.urihttps://doi.org/10.6002/ect.mesot2014.P137
dc.identifier.urihttps://hdl.handle.net/11616/96935
dc.identifier.volume13en_US
dc.identifier.wosWOS:000355058400061en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBaskent Univen_US
dc.relation.ispartofExperimental and Clinical Transplantationen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDextroseen_US
dc.subjectInsulinen_US
dc.subjectRecipienten_US
dc.subjectOperationen_US
dc.titleBlood Glucose Regulation During Living-Donor Liver Transplant Surgeryen_US
dc.typeConference Objecten_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu